NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation
P Van Damme, K Hole, A Pimenta-Marques… - PLoS …, 2011 - journals.plos.org
N-terminal acetylation (N-Ac) is a highly abundant eukaryotic protein modification.
Proteomics revealed a significant increase in the occurrence of N-Ac from lower to higher …
Proteomics revealed a significant increase in the occurrence of N-Ac from lower to higher …
Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms
OS Rathore, A Faustino, P Prudêncio, P Van Damme… - Scientific reports, 2016 - nature.com
Protein N-terminal acetylation is an ancient and ubiquitous co-translational modification
catalyzed by a highly conserved family of N-terminal acetyltransferases (NATs). Prokaryotes …
catalyzed by a highly conserved family of N-terminal acetyltransferases (NATs). Prokaryotes …
Protein N-terminal acetyltransferases: when the start matters
The majority of eukaryotic proteins are subjected to N-terminal acetylation (Nt-acetylation),
catalysed by N-terminal acetyltransferases (NATs). Recently, the structure of an NAT …
catalysed by N-terminal acetyltransferases (NATs). Recently, the structure of an NAT …
Spotlight on protein N-terminal acetylation
N-terminal acetylation (Nt-acetylation) is a widespread protein modification among
eukaryotes and prokaryotes alike. By appending an acetyl group to the N-terminal amino …
eukaryotes and prokaryotes alike. By appending an acetyl group to the N-terminal amino …
The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4
K Hole, P Van Damme, M Dalva, H Aksnes… - PloS one, 2011 - journals.plos.org
Protein Nα-terminal acetylation (Nt-acetylation) is considered one of the most common
protein modification in eukaryotes, and 80-90% of all soluble human proteins are modified in …
protein modification in eukaryotes, and 80-90% of all soluble human proteins are modified in …
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB
P Van Damme, M Lasa, B Polevoda… - Proceedings of the …, 2012 - National Acad Sciences
Protein N-terminal acetylation (Nt-acetylation) is an important mediator of protein function,
stability, sorting, and localization. Although the responsible enzymes are thought to be fairly …
stability, sorting, and localization. Although the responsible enzymes are thought to be fairly …
N-terminal acetylation and other functions of Nα-acetyltransferases
J Hollebeke, P Van Damme, K Gevaert - 2012 - degruyter.com
Protein N-terminal acetylation by Nα-acetyltransferases (NATs) is an omnipresent protein
modification that affects a large number of proteins. The exact biological role of N-terminal …
modification that affects a large number of proteins. The exact biological role of N-terminal …
Protein N-terminal acetylation: structural basis, mechanism, versatility, and regulation
S Deng, R Marmorstein - Trends in biochemical sciences, 2021 - cell.com
N-terminal acetylation (NTA) is one of the most widespread protein modifications, which
occurs on most eukaryotic proteins, but is significantly less common on bacterial and …
occurs on most eukaryotic proteins, but is significantly less common on bacterial and …
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans
T Arnesen, P Van Damme… - Proceedings of the …, 2009 - National Acad Sciences
Nα-terminal acetylation is one of the most common protein modifications in eukaryotes. The
COmbined FRActional DIagonal Chromatography (COFRADIC) proteomics technology that …
COmbined FRActional DIagonal Chromatography (COFRADIC) proteomics technology that …
Structure of a ternary Naa50p (NAT5/SAN) N-terminal acetyltransferase complex reveals the molecular basis for substrate-specific acetylation
G Liszczak, T Arnesen, R Marmorstein - Journal of Biological Chemistry, 2011 - ASBMB
The co-translational modification of N-terminal acetylation is ubiquitous among eukaryotes
and has been reported to have a wide range of biological effects. The human N-terminal …
and has been reported to have a wide range of biological effects. The human N-terminal …