Endoglin (CD105) is an integral membrane glycoprotein that serves as a coreceptor for
members of the transforming growth factor-β superfamily of proteins. A major role for …

The broad role of the transforming growth factor beta (TGFβ) signaling pathway in vascular
development, homeostasis, and repair is well appreciated. Endoglin is emerging as a novel …

Endoglin, a type-III accessory receptor for the Transforming Growth Factor (TGF)-β
superfamily pathway, is known for its crucial role during angiogenesis. Extensive work has …

Endoglin (CD105) is a type III auxiliary receptor for the transforming growth factor beta
(TGFβ) superfamily. Several lines of evidence suggest that endoglin plays a critical role in …

A soluble form of endoglin (sEng) is known to be an extracellular domain of the full-length
membrane endoglin, which is elevated during various pathological conditions related to …

The cellular expression, structure and function of endoglin, and its implication in several
vascular disorders remain enigmatic, even 30 years after its discovery. Endoglin (CD105) is …

Endoglin (CD 105, TGF-β receptor III) is a homodimeric transmembrane glycoprotein that
plays a regulatory role in TGF-β signaling. Its functional role in the context of atherosclerosis …

Endoglin is a transmembrane auxillary receptor for transforming growth factor-β (TGF-β) that
is predominantly expressed on proliferating endothelial cells. Endoglin deficient mice die …

Endoglin (CD105) is expressed on the surface of endothelial and haematopoietic cells in
mammals and binds TGFβ isoforms 1 and 3 in combination with the signaling complex of …

Following arterial occlusion, blood vessels respond by forming a new network of functional
capillaries (angiogenesis), by reorganizing preexisting capillaries through the recruitment of …