Effect of prostaglandin analogues on tear proteomics and expression of cytokines and matrix metalloproteinases in the conjunctiva and cornea

HYL Park, JH Kim, KM Lee, CK Park - Experimental eye research, 2012 - Elsevier
The purpose of this work was to identify potential tear-film-based proteins and their effect on
changes in the conjunctiva and cornea in eyes using prostaglandin (PG) analogues …

Change in prostaglandin expression levels and synthesizing activities in dry eye disease

J Shim, C Park, HS Lee, MS Park, HT Lim, S Chauhan… - Ophthalmology, 2012 - Elsevier
OBJECTIVE: To investigate the expression level of prostaglandins (PGs) and their de novo
synthesis in dry eye (DE) disease. DESIGN: Cross-sectional case-control study and in vivo …

[HTML][HTML] Tear biomarkers in latanoprost and bimatoprost treated eyes

S Reddy, P Sahay, D Padhy, S Sarangi, M Suar… - PLoS …, 2018 - journals.plos.org
Purpose Prostaglandin analogues (PGA's) are the mainstay and first line of treatment in
current glaucoma practise. Though latanoprost and bimatoprost are the most commonly …

[HTML][HTML] Proteomic profiling of inflammatory signaling molecules in the tears of patients on chronic glaucoma medication

TT Wong, L Zhou, J Li, L Tong, SZ Zhao… - … & visual science, 2011 - iovs.arvojournals.org
Purpose.: To identify the tear proteins associated with the long-term use of glaucoma
medication by using proteomic analysis and to compare these proteins to those previously …

Simultaneous study of matrix metalloproteinases, proinflammatory cytokines, and soluble cytokine receptors in the tears of noninfectious corneal ulcer patients

T Sakimoto, T Ohnishi, A Ishimori - Graefe's Archive for Clinical and …, 2014 - Springer
Background We investigated the presence of matrix metalloproteinases (MMPs), tissue
inhibitors of metalloproteinases (TIMPs), proinflammatory cytokines, and soluble cytokine …

Effects of topical nonsteroidal antiinflammatory drugs on the expression of matrix metalloproteinases in the cornea

VE Reviglio, TS Rana, QJ Li, FM Ashraf… - Journal of Cataract & …, 2003 - journals.lww.com
Purpose: To assess the effects of nonsteroidal antiinflammatory drug (NSAID) eyedrops on
the expression of matrix metalloproteinases in corneal tissue. Setting: Ocular Microbiology …

Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye

CS De Paiva, RM Corrales, AL Villarreal… - Experimental eye …, 2006 - Elsevier
We investigated the effects of corticosteroid and doxycycline on expression of matrix
metalloproteinase (MMP)-9 and inflammatory cytokines and activation of mitogen-activated …

Cytokine and lipid inflammatory mediator profile of human tears during contact lens associated inflammatory diseases

A Thakur, MDP Willcox - Experimental eye research, 1998 - Elsevier
Contact lens induced acute red eye (CLARE) and contact lens induced peripheral ulcer
(CLPU) are among the most common contact lens induced inflammatory reactions. Both …

[HTML][HTML] Lipid-modifying enzymes in human tear fluid and corneal epithelial stress response

A Robciuc, AH Rantamäki… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: Since homeostasis at the ocular surface requires a delicate balance between
numerous factors, and the external environment contributes as an unpredictable component …

[HTML][HTML] Tear proteomics in keratoconus

C Pannebaker, HL Chandler, JJ Nichols - Molecular Vision, 2010 - ncbi.nlm.nih.gov
Purpose The purpose of this work was to identify potential tear-film based proteins
expressed in keratoconus. Methods R ecruited subjects were normal gas permeable (GP) …