Targeted therapy for rare lung cancers: Status, challenges, and prospects

C Wang, X Yuan, J Xue - Molecular Therapy, 2023 - cell.com
Lung cancer causes the most cancer-related deaths worldwide. In recent years, molecular
and immunohistochemical techniques have rapidly developed, further inaugurating an era …

Rare molecular subtypes of lung cancer

G Harada, SR Yang, E Cocco, A Drilon - Nature Reviews Clinical …, 2023 - nature.com
Oncogenes that occur in≤ 5% of non-small-cell lung cancers have been defined as 'rare';
nonetheless, this frequency can correspond to a substantial number of patients diagnosed …

[HTML][HTML] Targeted therapies in non-small cell lung cancer: present and future

J McLaughlin, J Berkman, P Nana-Sinkam - Faculty Reviews, 2023 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of malignancy-related death in the United States and the
second most common cancer diagnosis worldwide. In the last two decades, lung cancer …

Cutting-Edge Therapies for Lung Cancer

AS La'ah, SH Chiou - Cells, 2024 - mdpi.com
Lung cancer remains a formidable global health challenge that necessitates inventive
strategies to improve its therapeutic outcomes. The conventional treatments, including …

Beyond adenocarcinoma: current treatments and future directions for squamous, small cell, and rare lung cancer histologies

DE Gerber, PK Paik, A Dowlati - American Society of Clinical …, 2015 - ascopubs.org
Lung cancer encompasses a diverse spectrum of histologic subtypes. Until recently, the
majority of therapeutic advances were limited to the minority of patients with …

Lung cancer genomics in the era of accelerated targeted drug development

P Wijesinghe, A Bollig-Fischer - Lung Cancer and Personalized Medicine …, 2016 - Springer
Lung cancer is the leading cause of cancer-related deaths in the United States and the 5-
year overall survival outlook for a patient has not improved in several decades. Recently …

Targeted therapies for lung cancer: clinical experience and novel agents

JE Larsen, T Cascone, DE Gerber… - The Cancer …, 2011 - journals.lww.com
Although lung cancer remains the leading cancer killer in the United States, recently a
number of developments indicate future clinical benefit. These include evidence that …

Targeted therapies for lung cancer: how did the game begin?

NI Kanellakis, T Jacinto, I Psallidas - Breathe, 2016 - Eur Respiratory Soc
Lung cancer is the leading cause of cancer death worldwide, causing 1.4 million deaths
annually [1]. Patients with advanced stage nonsmall cell lung cancer (NSCLC) are usually …

Molecular diagnosis and targeting for lung cancer

K Yoneda, F Tanaka - Molecular diagnosis and targeting for thoracic and …, 2018 - Springer
Lung cancer is the leading cause of cancer deaths associated with poor prognosis. Patients
with advanced lung cancer had been “uniformly” treated with platinum-based cytotoxic …

emerging therapeutic targets in non–small cell lung cancer

GK Dy, AA Adjei - Proceedings of the American Thoracic Society, 2009 - atsjournals.org
Over the last decade, systemic cancer therapies have evolved to exploit the growing
knowledge of molecular aberrations involved in the development and progression of lung …