[PDF][PDF] Fecal microbial transplant capsules are safe in hepatic encephalopathy: a phase 1, randomized, placebo‐controlled trial
Hepatic encephalopathy (HE) can cause major morbidity despite standard of care (SOC;
rifaximin/lactulose). Fecal microbial transplant (FMT) enemas postantibiotics are safe, but …
rifaximin/lactulose). Fecal microbial transplant (FMT) enemas postantibiotics are safe, but …
[PDF][PDF] Fecal microbiota transplant improves cognition in hepatic encephalopathy and its effect varies by donor and recipient
PP Bloom, J Donlan, M Torres Soto… - Hepatology …, 2022 - Wiley Online Library
Early data suggest fecal microbiota transplant (FMT) may treat hepatic encephalopathy (HE).
Optimal FMT donor and recipient characteristics are unknown. We assessed the safety and …
Optimal FMT donor and recipient characteristics are unknown. We assessed the safety and …
Gut microbiota modulation and fecal transplantation: an overview on innovative strategies for hepatic encephalopathy treatment
R Hassouneh, JS Bajaj - Journal of Clinical Medicine, 2021 - mdpi.com
Simple Summary Treatment of advanced liver disease and its complications continue to be a
challenge due to the complexity of this illness. In recent years, the gut microbiome has been …
challenge due to the complexity of this illness. In recent years, the gut microbiome has been …
[PDF][PDF] Fecal microbiota transplant from a rational stool donor improves hepatic encephalopathy: a randomized clinical trial
Recurrent hepatic encephalopathy (HE) is a leading cause of readmission despite standard
of care (SOC) associated with microbial dysbiosis. Fecal microbiota transplantation (FMT) …
of care (SOC) associated with microbial dysbiosis. Fecal microbiota transplantation (FMT) …
Fecal microbiota transplantation in hepatic encephalopathy: a systematic review
Hepatic encephalopathy (HE) is a reversible neurocognitive dysfunction that ranges in
severity from subclinical alterations to coma. Patients with chronic liver disease are …
severity from subclinical alterations to coma. Patients with chronic liver disease are …
[HTML][HTML] Microbial functional change is linked with clinical outcomes after capsular fecal transplant in cirrhosis
BACKGROUND Hepatic encephalopathy (HE) is associated with poor outcomes. A prior
randomized, pilot trial demonstrated safety after oral capsular fecal microbial transplant …
randomized, pilot trial demonstrated safety after oral capsular fecal microbial transplant …
Fecal microbiota transplantation in the management of hepatic encephalopathy
Discussion To our knowledge, this is the first report of treating HE with FMT. In this case, the
dramatic clinical improvements, both subjectively and objectively, following serial FMT are …
dramatic clinical improvements, both subjectively and objectively, following serial FMT are …
[HTML][HTML] Long-term outcomes after fecal microbiota transplant in cirrhosis
Methods: For rational donor selection, the microbiome profile of HE patients and healthy
controls were assessed. HE patients demonstrated a relative reduction of Lachnospiraceae …
controls were assessed. HE patients demonstrated a relative reduction of Lachnospiraceae …
[PDF][PDF] Fecal microbiota transplant in cirrhosis reduces gut microbial antibiotic resistance genes: analysis of two trials
JS Bajaj, A Shamsaddini, A Fagan… - Hepatology …, 2021 - Wiley Online Library
Antibiotic resistance leads to poor outcomes in cirrhosis. Fecal microbiota transplant (FMT)
is associated with reduction in antibiotic resistance gene (ARG) burden in patients without …
is associated with reduction in antibiotic resistance gene (ARG) burden in patients without …
[PDF][PDF] Neuroinflammation in murine cirrhosis is dependent on the gut microbiome and is attenuated by fecal transplant
R Liu, JD Kang, RB Sartor, M Sikaroodi, A Fagan… - …, 2020 - Wiley Online Library
Cirrhosis and hepatic encephalopathy (HE) is associated with an altered gut–liver–brain
axis. Fecal microbial transplant (FMT) after antibiotics improves outcomes in HE, but the …
axis. Fecal microbial transplant (FMT) after antibiotics improves outcomes in HE, but the …