Identification of trans-2-cis-8-Matricaria-ester from the Essential Oil of Erigeron multiradiatus and Evaluation of Its Antileishmanial Potential by in Vitro and in Silico …

S Chandra Pandey, DS Dhami, A Jha… - ACS …, 2019 - ACS Publications
The essential oil (EO) composition of the aerial parts of Erigeron multiradiatus (Lindl. ex DC.)
Benth growing wild in the central Himalayan region of Uttarakhand, India, was analyzed by …

Antileishmanial activity of essential oil from a high-altitude herb, Heracleum pinnatum: an in vitro and in silico analysis

R Chuskit, J Joshi, I Gupta, C Bandral… - Journal of Essential …, 2024 - Taylor & Francis
Heracleum pinnatum, an aromatic herb, is used as a traditional medicine in the Amchi
system of Trans-Himalayan Ladakh (India). The study evaluates the leishmanicidal and …

Promising Antileishmanial Activity of Micromeria nervosa Essential Oil: In Vitro and In Silico Studies

R Essid, S Kefi, B Damergi, G Abid, N Fares, S Jallouli… - Molecules, 2024 - mdpi.com
The present study aimed to evaluate the leishmanicidal potential of the essential oil (EO) of
Micromeria (M.) nervosa and to investigate its molecular mechanism of action by qPCR …

Oleanolic acid (OA) as an antileishmanial agent: Biological evaluation and in silico mechanistic insights

TS Melo, CR Gattass, DC Soares, MR Cunha… - Parasitology …, 2016 - Elsevier
Although a worldwide health problem, leishmaniasis is considered a highly neglected
disease, lacking efficient and low toxic treatment. The efforts for new drug development are …

Anti-Leishmania amazonensis Activity, Cytotoxic Features, and Chemical Profile of Allium sativum (Garlic) Essential Oil

AR Garcia, MMB Amorim, ACF Amaral… - Tropical Medicine and …, 2023 - mdpi.com
Human tegumentary leishmaniasis (HTL) is a serious tropical disease caused by
Leishmania amazonensis. Developing new leishmanicidal agents can help overcome …

Leishmanicidal activities of Artemisia annua leaf essential oil against Visceral Leishmaniasis

M Islamuddin, G Chouhan, MY Want, M Tyagi… - Frontiers in …, 2014 - frontiersin.org
Visceral leishmaniasis (VL), the second-most dreaded parasitic disease after malaria, is
currently endemic in 88 countries. Dramatic increases in the rates of infection, drug …

The cytotoxic and anti-leishmanial activity of Oregano (Origanum vulgare) essential oil: An in vitro, in vivo, and in silico study

F Tomiotto-Pellissier, BT da Silva Bortoleti… - Industrial Crops and …, 2022 - Elsevier
This study was aimed at investigating the leishmanicidal and immunomodulatory of oregano
essential oil (OEO) from Origanum vulgare on experimental Leishmania amazonensis …

Essential‐Oil Composition, Antileishmanial, and Toxicity Study of Artemisia abyssinica and Satureja punctata ssp. punctata from Ethiopia

Y Tariku, A Hymete, A Hailu… - Chemistry & Biodiversity, 2010 - Wiley Online Library
Essential oils of Artemisia abyssinica and Satureja punctata ssp. punctata from Ethiopia
were analyzed by GC and GC/MS, and screened for leishmanicidal activity against …

Potential Effects of Essential Oil from Plinia cauliflora (Mart.) Kausel on Leishmania: In Vivo, In Vitro, and In Silico Approaches

VN Holanda, TGS Brito, JRS Oliveira, RX Cunha… - Microorganisms, 2024 - mdpi.com
In the search for new chemotherapeutic alternatives for cutaneous leishmaniasis (CL),
essential oils are promising due to their diverse biological potential. In this study, we aimed …

Leishmanicidal and cytotoxic activity of essential oil from the fruit peel of Myrciaria floribunda (H. West ex Willd.) O. Berg: Molecular docking and molecular dynamics simulations …

DCS Barbosa, VN Holanda, A Ghosh… - Journal of …, 2022 - Taylor & Francis
Cutaneous Leishmaniasis (CL) is a neglected disease characterized by highest morbidity
rates worldwide. The available treatment for CL has several limitations including serious …