Rho-associated coiled-coil containing kinases (ROCK) were originally identified as effectors
of the RhoA small GTPase.–They belong to the AGC family of serine/threonine kinases and …

A Rho-associated coiled-coil kinase (ROCK) is identified as a critical downstream effector of
GTPase RhoA which contains two isoforms, ROCK1 (also known as p160ROCK and ROKβ) …

Abstract The small Rho GTPase family of proteins, encompassing the three major G-protein
classes Rho, Rac and cell division control protein 42, are key mitogenic signaling molecules …

Rho-associated kinases ROCK1 and ROCK2 are key regulators of actin cytoskeleton
dynamics downstream of Rho GTPases that participate in the control of important …

Remarkable progress has been made in understanding effector molecules of small GTPase
Rho, especially Rho-associated kinase (Rho-kinase/ROK/ROCK), in the past 5 years. Rho …

Rho‐associated kinase (Rho‐kinase/ROCK/ROK) is an effector of the small GTPase Rho
and belongs to the AGC family of kinases. Rho‐kinase has pleiotropic functions including …

Rho kinases (ROCKs) are the first and the best-characterized effectors of the small G-protein
RhoA. In addition to their effect on actin organization, or through this effect, ROCKs have …

ROCK or Rho-associated kinase, a serine/threonine kinase, is an effector of Rho-dependent
signaling and is involved in actin-cytoskeleton assembly and cell motility and contraction …

Rho-associated kinases ROCK1 and ROCK2 are serine/threonine kinases that are
downstream targets of the small GTPases RhoA, RhoB, and RhoC. ROCKs are involved in …

Rho kinase (ROCK) belongs to a family of serine/threonine kinases that are activated via
interaction with Rho GTPases. ROCK is involved in a wide range of fundamental cellular …