Macrophage is a very promising cell type for cancer immunotherapy, yet it is difficult to
obtain enough functional macrophages for clinical cell therapy. Herein, we descibe a …

Induced pluripotent stem cells (iPSCs) are a type of cells similar to embryonic stem cells but
produced by reprogramed somatic cells. Through in vitro differentiation of iPSCs, we can …

Macrophages are present in most vertebrate tissues and comprise widely dispersed and
heterogeneous cell populations with different functions. They are key players in health and …

Background: Pluripotent stem cells, including induced pluripotent stem cells (iPSCs), have
the capacity to differentiate towards all three germ layers and have been highlighted as an …

Macrophages are pivotal effectors of host immunity and regulators of tissue homeostasis.
Understanding of human macrophage biology has been hampered by the lack of reliable …

Macrophages play important roles in many diseases. We describe a protocol and the
associated resources for the differentiation of human induced pluripotent stem cell‐derived …

A major challenge in studies of human diseases involving macrophages is low yield and
heterogeneity of the primary cells and limited ability of these cells for transfections and …

Monocytes and macrophages are essential for immune defense and tissue hemostasis.
They are also the underlying trigger of many diseases. The availability of robust and short …

Mouse and human pluripotent stem cells have been widely used to study the development
of the hematopoietic and immune systems. Although not all cells can be derived with the …

Human macrophages are specialised hosts for HIV-1, dengue virus, Leishmania and
Mycobacterium tuberculosis. Yet macrophage research is hampered by lack of appropriate …