Pressurized metered dose inhalers (MDIs) are a long-standing method to treat diseases of
the lung, such as asthma and chronic obstructive pulmonary disease. MDIs rely on the …

Pressurized metered dose inhalers (MDIs) were first introduced in the 1950s and they are
currently widely prescribed as portable systems to treat pulmonary conditions. MDIs consist …

The phase-out of chlorofluorocarbons (CFCs) has spurred the development of alternative
pulmonary drug delivery systems to pressurized metered dose inhalers (MDIs), such as dry …

Interest in the use of solution inhalers and dry powder inhalers (DPIs) has increased in
recent years, broadening from systems for the delivery of traditional respiratory medications …

Technologies for long-term delivery of aerosol medications in asthma and chronic
obstructive pulmonary disease have improved over the past 2 decades with advancements …

Pressurized metered-dose inhalers (pMDIs) are sometimes viewed as old-fashioned and as
having been superseded by dry powder inhalers (DPIs). Here, we review the technological …

There are a multitude of formulation factors to consider when developing a pMDI. Evaluation
of each of these variables has been performed over the years, but there has been an …

Recent advances in aerosolization technology have led to renewed interest in pulmonary
delivery of a variety of drugs. Pressurized metered dose inhalers (pMDIs) and dry powder …

Unit dose inhalation aerosols fail to achieve optimal lung deposition even though this can be
achieved by dispersing 1-5 µm aerodynamic diameter particles in air. Dry powder …

The pressurised metered-dose inhaler (pMDI) has now been available for 50 years. Once
regarded as an inefficient and difficult-to-use device, the technology has evolved …