Neuropharmacology in traumatic brain injury: from preclinical to clinical neuroprotection?
D Lerouet, C Marchand‐Leroux… - Fundamental & clinical …, 2021 - Wiley Online Library
Traumatic brain injury (TBI) constitutes a major health problem worldwide and is a leading
cause of death and disability in individuals, contributing to devastating socioeconomic …
cause of death and disability in individuals, contributing to devastating socioeconomic …
Targets of neuroprotection and review of pharmacological interventions in traumatic brain injury
MI Hiskens - Journal of Pharmacology and Experimental …, 2022 - ASPET
Traumatic brain injury (TBI) is a major contributor to disability and death worldwide, and
manifests in cognitive, behavioral, and motor impairment. Although there have been …
manifests in cognitive, behavioral, and motor impairment. Although there have been …
Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies
Traumatic brain injury (TBI) causes secondary biochemical changes that contribute to
subsequent tissue damage and associated neuronal cell death. Neuroprotective treatments …
subsequent tissue damage and associated neuronal cell death. Neuroprotective treatments …
Neuroprotection for traumatic brain injury
Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Despite
extensive preclinical research supporting the effectiveness of neuroprotective therapies for …
extensive preclinical research supporting the effectiveness of neuroprotective therapies for …
Exploring new routes for neuroprotective drug development in traumatic brain injury
T Janowitz, DK Menon - Science translational medicine, 2010 - science.org
Worldwide, traumatic brain injury (TBI) is a major cause of mortality and morbidity with a
substantial predicted increase in incidence. Despite an obvious need, there are no …
substantial predicted increase in incidence. Despite an obvious need, there are no …
Evaluation of pharmacological treatment strategies in traumatic brain injury
N Marklund, A Bakshi, DJ Castelbuono… - Current …, 2006 - ingentaconnect.com
Traumatic brain injury (TBI) is a devastating disease, predominantely affecting young
people. Although the prognosis for TBI victims has improved in recent years, many survivors …
people. Although the prognosis for TBI victims has improved in recent years, many survivors …
Emerging treatments for traumatic brain injury
Y Xiong, A Mahmood, M Chopp - Expert opinion on emerging drugs, 2009 - Taylor & Francis
Background: This review summarizes promising approaches for the treatment of traumatic
brain injury (TBI) that are in either preclinical or clinical trials. Objective: The …
brain injury (TBI) that are in either preclinical or clinical trials. Objective: The …
Neuroprotective agents in traumatic brain injury
AIR Maas - Expert opinion on investigational drugs, 2001 - Taylor & Francis
The role of neuroprotection in traumatic brain injury (TBI) is reviewed. Basic research and
experimental investigations have identified many different compounds with potential …
experimental investigations have identified many different compounds with potential …
Neuroprotection in traumatic brain injury: a complex struggle against the biology of nature
JW Schouten - Current opinion in critical care, 2007 - journals.lww.com
Traumatic brain injury is a complex disease, and development of clinically effective
neuroprotective agents is a difficult task. Experimental traumatic brain injury has provided …
neuroprotective agents is a difficult task. Experimental traumatic brain injury has provided …
[HTML][HTML] Neuroprotective strategies for traumatic brain injury: improving clinical translation
Traumatic brain injury (TBI) induces secondary biochemical changes that contribute to
delayed neuroinflammation, neuronal cell death, and neurological dysfunction. Attenuating …
delayed neuroinflammation, neuronal cell death, and neurological dysfunction. Attenuating …
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