Aging is a physiological and progressive phenomenon in all organisms' life cycle,
characterized by the accumulation of degenerative processes triggered by several …

A-to-I editing is an adenosine-to-inosine modification of mRNA particularly widespread in
the human brain, where it affects thousands of genes. A growing body of evidence suggests …

The study of modified RNA known as epitranscriptomics has become increasingly relevant
in our understanding of disease-modifying mechanisms. Methylation of N6 adenosine (m 6 …

RNA editing is a post-transcriptional process, which results in base substitution
modifications to RNA. It is an important process in generating protein diversity through …

Distinct cell types are generated at specific times during brain development and are
regulated by epigenetic, transcriptional, and newly emerging epitranscriptomic mechanisms …

RNA editing is an alteration in the primary nucleotide sequences resulting from a chemical
change in the base. RNA editing is observed in eukaryotic mRNA, transfer RNA, ribosomal …

RNA methylation participates in the functional regulation of various biological processes,
affecting RNA translocation, alternative splicing, maturation, stability, and degradation to …

RNA modifications are dynamic and reversible chemical modifications on substrate RNA
that are regulated by specific modifying enzymes. They play important roles in the regulation …

The importance of epitranscriptomics in regulating gene expression has received
widespread attention. Recently, RNA methylation modifications, particularly N6 …

The brain is one of the organs that are preferentially targeted by adenosine-to-inosine (A-to-
I) RNA editing, a posttranscriptional modification. This chemical modification affects …