[HTML][HTML] Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options

JCO Sardi, L Scorzoni, T Bernardi… - Journal of medical …, 2013 - microbiologyresearch.org
The incidence of fungal infections has increased significantly, so contributing to morbidity
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …

[HTML][HTML] Biofilm Formation in Medically Important Candida Species

Z Malinovská, E Čonková, P Váczi - Journal of Fungi, 2023 - mdpi.com
Worldwide, the number of infections caused by biofilm-forming fungal pathogens is very
high. In human medicine, there is an increasing proportion of immunocompromised patients …

Our current clinical understanding of Candida biofilms: where are we two decades on?

G Ramage, E Borghi, CF Rodrigues, R Kean… - APMIS, 2023 - Wiley Online Library
Clinically we have been aware of the concept of Candida biofilms for many decades, though
perhaps without the formal designation. Just over 20 years ago the subject emerged on the …

Future directions for anti-biofilm therapeutics targeting Candida

JE Nett - Expert review of anti-infective therapy, 2014 - Taylor & Francis
While proliferating in its most common mode of growth, a biofilm, Candida spp. exhibit
increased resistance to available antifungal agents. These adherent communities are …

[HTML][HTML] Candida spp./Bacteria Mixed Biofilms

ME Rodrigues, F Gomes, CF Rodrigues - Journal of Fungi, 2019 - mdpi.com
The ability to form biofilms is a common feature of microorganisms, such as bacteria or fungi.
These consortiums can colonize a variety of surfaces, such as host tissues, dentures, and …

The effect of biomaterials and antifungals on biofilm formation by Candida species: a review

M Cuéllar-Cruz, A Vega-González… - European journal of …, 2012 - Springer
Candida albicans, C. glabrata, C. parapsilosis, and C. tropicalis are able to form biofilms on
virtually any biomaterial implanted in a human host. Biofilms are a primary cause of mortality …

Candida biofilms and their role in infection

LJ Douglas - Trends in microbiology, 2003 - cell.com
Pathogenic fungi in the genus Candida can cause both superficial and serious systemic
disease, and are now recognized as major agents of hospital-acquired infection. Many …

[HTML][HTML] Natural Compounds: A Hopeful Promise as an Antibiofilm Agent Against Candida Species

A Shariati, M Didehdar, S Razavi, M Heidary… - Frontiers in …, 2022 - frontiersin.org
The biofilm communities of Candida are resistant to various antifungal treatments. The ability
of Candida to form biofilms on abiotic and biotic surfaces is considered one of the most …

Candida Biofilms: an Update

G Ramage, SP Saville, DP Thomas… - Eukaryotic cell, 2005 - Am Soc Microbiol
Our classical perception of microorganisms as unicellular life forms is almost entirely based
on the pure-culture mode of growth; since microbial suspensions can be diluted to a single …

[HTML][HTML] Antifungal therapy of Candida biofilms: Past, present and future

OH Ajetunmobi, H Badali, JA Romo, G Ramage… - Biofilm, 2023 - Elsevier
Virtually all Candida species linked to clinical candidiasis are capable of forming highly
resistant biofilms on different types of surfaces, which poses an additional significant threat …