Immunoregulation and clinical significance of neutrophils/NETs-ANGPT2 in tumor microenvironment of gastric cancer

S Yang, X Zou, J Li, H Yang, A Zhang, Y Zhu… - Frontiers in …, 2022 - frontiersin.org
Although significant progress has been made in the study of gastric cancer (GC), clinicians
lack reliable protein markers for accurate diagnosis and tumor stratification. Neutrophil …

Neutrophil extracellular traps promote angiogenesis in gastric cancer

S Yang, B Sun, J Li, N Li, A Zhang, X Zhang… - Cell Communication and …, 2023 - Springer
Although antiangiogenic therapy has been used in gastric cancer, disease progression due
to drug resistance remains common. Neutrophils play an important role in the occurrence …

[HTML][HTML] Neutrophil extracellular traps in gastrointestinal cancer

ZQ Chu, KC Zhang, L Chen - World journal of gastroenterology, 2021 - ncbi.nlm.nih.gov
Gastrointestinal (GI) cancer is a high-risk malignancy and is characterized by high mortality
and morbidity worldwide. Neutrophil extracellular traps (NETs), a weblike structure …

A novel neutrophil extracellular traps signature for overall survival prediction and tumor microenvironment identification in gastric cancer

Z Qu, Y Han, Q Zhu, W Ding, Y Wang… - Journal of …, 2023 - Taylor & Francis
Background Neutrophil extracellular traps (NETs) released by neutrophils are crucial for
cancer development, metastasis, and can indicate gastric cancer (GC) patients' prognosis …

Emerging Role of Neutrophil Extracellular Traps in Gastrointestinal Tumors: A Narrative Review

Y Zhang, J Song, Y Zhang, T Li, J Peng, H Zhou… - International Journal of …, 2022 - mdpi.com
Neutrophil extracellular traps (NETs) are extracellular fibrous networks consisting of
depolymerized chromatin DNA skeletons with a variety of antimicrobial proteins. They are …

TF/PAR2 Signaling Axis Supports the Protumor Effect of Neutrophil Extracellular Traps (NETs) on Human Breast Cancer Cells

K Martins-Cardoso, A Maçao, JL Souza, AG Silva… - Cancers, 2023 - mdpi.com
Simple Summary Neutrophil extracellular traps (NETs) contribute to tumor progression at
different stages, such as primary growth, metastasis, angiogenesis, and cancer-associated …

[HTML][HTML] A signature for pan-cancer prognosis based on neutrophil extracellular traps

Y Zhang, L Guo, Q Dai, B Shang, T Xiao… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Neutrophil extracellular traps (NETs) were originally thought to be formed by
neutrophils to trap invading microorganisms as a defense mechanism. Increasing studies …

Neutrophil extracellular traps induced by the hypoxic microenvironment in gastric cancer augment tumour growth

J Li, Y Xia, B Sun, N Zheng, Y Li, X Pang… - Cell Communication and …, 2023 - Springer
Background Inflammation-related predisposition to cancer plays an essential role in cancer
progression and is associated with poor prognosis. A hypoxic microenvironment and …

Neutrophil extracellular traps in digestive cancers: warrior or accomplice

Y Chen, L Han, X Qiu, G Wang, J Zheng - Frontiers in Oncology, 2021 - frontiersin.org
Characterized as a complex of extracellular DNA fibers and granule proteins, neutrophil
extracellular traps (NETs) are generated specifically by neutrophils which play a critical role …

Effect of NETs/COX-2 pathway on immune microenvironment and metastasis in gastric cancer

A Zhang, X Zou, S Yang, H Yang, Z Ma, J Li - Frontiers in Immunology, 2023 - frontiersin.org
Background Neutrophil extracellular traps (NETs) are crucial in the progression of several
cancers. The formation of NETs is closely related to reactive oxygen species (ROS), and the …