Design considerations for liposomal vaccines: influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens

DS Watson, AN Endsley, L Huang - Vaccine, 2012 - Elsevier
Liposomes (phospholipid bilayer vesicles) are versatile and robust delivery systems for
induction of antibody and T lymphocyte responses to associated subunit antigens. In the last …

Liposomes used as a vaccine adjuvant-delivery system: From basics to clinical immunization

N Wang, M Chen, T Wang - Journal of Controlled Release, 2019 - Elsevier
Liposomes are widely utilized as a carrier to improve therapeutic efficacy of agents thanks to
their merits of high loading capacity, targeting delivery, reliable protection of agents, good …

Liposomes as a vaccine delivery system

N Marasini, KA Ghaffar, M Skwarczynski… - Micro and Nanotechnology …, 2017 - Elsevier
Among the various particulate delivery systems, liposomes—bubble-like nano/microsized
lipidic bilayer structures—have shown great promise as an antigen-carrying vehicle. Few …

Cationic liposomes as vaccine adjuvants

D Christensen, KS Korsholm, I Rosenkrands… - Expert review of …, 2007 - Taylor & Francis
Cationic liposomes are lipid-bilayer vesicles with a positive surface charge that have re-
emerged as a promising new adjuvant technology. Although there is some evidence that …

Liposomal vaccine delivery systems

M Henriksen-Lacey, KS Korsholm… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Liposomes remain at the forefront of drug and vaccine design owing to their
well-documented abilities to act as delivery vehicles. Nevertheless, the concept of liposomes …

Liposome-based delivery system for vaccine candidates: constructing an effective formulation

AK Giddam, M Zaman, M Skwarczynski, I Toth - Nanomedicine, 2012 - Taylor & Francis
The discovery of liposomes in 1965 by Bangham and coworkers changed the prospects of
drug delivery systems. Since then, the application of liposomes as vaccine delivery systems …

Designing liposomal adjuvants for the next generation of vaccines

Y Perrie, F Crofts, A Devitt, HR Griffiths… - Advanced drug delivery …, 2016 - Elsevier
Liposomes not only offer the ability to enhance drug delivery, but can effectively act as
vaccine delivery systems and adjuvants. Their flexibility in size, charge, bilayer rigidity and …

[HTML][HTML] Liposomes: from biophysics to the design of peptide vaccines

F Frezard - Brazilian Journal of Medical and Biological Research, 1999 - SciELO Brasil
Liposomes (lipid-based vesicles) have been widely studied as drug delivery systems due to
their relative safety, their structural versatility concerning size, composition and bilayer …

[HTML][HTML] Liposome-based adjuvants for subunit vaccines: formulation strategies for subunit antigens and immunostimulators

S Tandrup Schmidt, C Foged, K Smith Korsholm… - Pharmaceutics, 2016 - mdpi.com
The development of subunit vaccines has become very attractive in recent years due to their
superior safety profiles as compared to traditional vaccines based on live attenuated or …

Cationic liposomes as vaccine adjuvants

D Christensen, KS Korsholm, P Andersen… - Expert review of …, 2011 - Taylor & Francis
The application of cationic liposomes as vaccine delivery systems and adjuvants has been
investigated extensively over the last few decades. However, cationic liposomes are, in …