From influenza to COVID-19: Lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases
Vaccination represents the best line of defense against infectious diseases and is crucial in
curtailing pandemic spread of emerging pathogens to which a population has limited …
curtailing pandemic spread of emerging pathogens to which a population has limited …
Non-immunotherapy application of LNP-mRNA: Maximizing efficacy and safety
I Vlatkovic - Biomedicines, 2021 - mdpi.com
Lipid nanoparticle (LNP) formulated messenger RNA-based (LNP-mRNA) vaccines came
into the spotlight as the first vaccines against SARS-CoV-2 virus to be applied worldwide …
into the spotlight as the first vaccines against SARS-CoV-2 virus to be applied worldwide …
A comprehensive review of mRNA vaccines
mRNA vaccines have been demonstrated as a powerful alternative to traditional
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …
Principles for designing an optimal mRNA lipid nanoparticle vaccine
mRNA Lipid nanoparticles (LNPs) have recently been propelled onto the center stage of
therapeutic platforms due to the success of the SARS-CoV-2 mRNA LNP vaccines (mRNA …
therapeutic platforms due to the success of the SARS-CoV-2 mRNA LNP vaccines (mRNA …
Future considerations for the mRNA-lipid nanoparticle vaccine platform
BZ Igyártó, S Jacobsen, S Ndeupen - Current opinion in virology, 2021 - Elsevier
Vaccines based on mRNA-containing lipid nanoparticles (LNPs) pioneered by Katalin
Karikó and Drew Weissman at the University of Pennsylvania are a promising new vaccine …
Karikó and Drew Weissman at the University of Pennsylvania are a promising new vaccine …
Lipid nanoparticles as delivery systems for RNA-based vaccines
BN Aldosari, IM Alfagih, AS Almurshedi - Pharmaceutics, 2021 - mdpi.com
There has been increased interest in the development of RNA-based vaccines for protection
against various infectious diseases and also for cancer immunotherapies. Rapid and cost …
against various infectious diseases and also for cancer immunotherapies. Rapid and cost …
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
N Chaudhary, D Weissman… - Nature reviews Drug …, 2021 - nature.com
Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …
The immunostimulatory nature of mRNA lipid nanoparticles
Abstract mRNA-Lipid nanoparticles (LNPs) are at the forefront of global medical research.
With the development of mRNA-LNP vaccines to combat the COVID-19 pandemic, the …
With the development of mRNA-LNP vaccines to combat the COVID-19 pandemic, the …
Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine
Lipid nanoparticle (LNP)-formulated nucleoside-modified mRNA vaccines have proven to be
very successful in the fight against the coronavirus disease 2019 (COVID-19) pandemic …
very successful in the fight against the coronavirus disease 2019 (COVID-19) pandemic …
Lipid nanoparticles as promising carriers for mRNA vaccines for viral lung infections
M Hajiaghapour Asr, F Dayani, F Saedi Segherloo… - Pharmaceutics, 2023 - mdpi.com
In recent years, there has been an increase in deaths due to infectious diseases, most
notably in the context of viral respiratory pathogens. Consequently, the focus has shifted in …
notably in the context of viral respiratory pathogens. Consequently, the focus has shifted in …
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