Oxycodone is a semi-synthetic opioid derived from thebaine. Global consumption of
oxycodone has surpassed that of morphine, which was for long considered as the 'gold …

Background Parenteral opioids are used for pain relief in labour but there are little data for
oxycodone in this context. The aim of this study was to evaluate the efficacy, foetal exposure …

Physiological changes during pregnancy may change pharmacokinetics of compounds.
Oxycodone is an increasingly used opioid agonist in acute pain management but its …

Introduction There are limited data on oxycodone pharmacokinetics during pregnancy and
on fetal exposure after maternal administration. The present study describes the …

Aims Both effective analgesia and early breastfeeding play an important role in maternal
and neonatal well‐being after Caesarean delivery. We studied controlled‐release …

Oxycodone is commonly used by pregnant women for the treatment of pain. However, the
potential risk associated with its use in pregnancy have not been robustly evaluated. The …

The main sites of the analgesic action of oxycodone are the brain and spinal cord. The
present study describes the concentrations of oxycodone and its metabolites in the brain …

Background: Oxycodone has become popular for post‐Caesarean section (CS) analgesia
yet it is not currently recommended for use in breast‐feeding mothers because of limited …

Methods Eighty women (40+ 40) were scheduled for elective CS under spinal anaesthesia.
All patients received postoperative multimodal analgesic therapy, including ibuprofen and …

Introduction Opioids are used for pain relief during the first stage of labor. Oxycodone can
cause maternal hypotension that may modify utero‐and fetoplacental circulatory physiology …