The aim of this study was to investigate the role of the XRCC1 Arg399Gln polymorphism in
the susceptibility of a Kashmiri population to colorectal cancer (CRC). We investigated the …

Background: The DNA repair gene XRCC1Arg399Gln gene polymorphism has been found
to be implicated in the development of various cancers, including colorectal cancer (CRC) …

Background The risk of sporadic colorectal cancer can be associated with environmental
and lifestyle factors that may be sources of physical and chemical carcinogens, modulated …

XRCC2 is an essential part of the homologous recombination repair pathway. However,
relatively little is known about the effect of XRCC2 gene C41657T and G4234C …

Previous studies investigating the association between X-ray repair cross-complementation
group 1 (XRCC1) Arg399Gln polymorphism and colorectal cancer risk in Chinese provided …

Purpose Studies on polymorphism of X-ray repair cross-complementing group 1 (XRCC1),
group 3 (XRCC3), and colorectal cancer risk are inconclusive. The purpose of this study is to …

Purpose Previous studies investigating the association between X-ray repair cross-
complementation group 1 (XRCC1) polymorphisms and colorectal cancer (CRC) risk has …

X-ray repair cross-complementing group 1 (XRCC1) plays a key role in DNA repair, genetic
instability, and tumorigenesis. The XRCC1 R399Q polymorphism has been reported in …

Background: Non-synonymous polymorphisms in XRCC1 hase been shown to reduce
effectiveness of DNA repair and be associated with risk of certain cancers. In this study we …

Several potential functional polymorphisms in the DNA repair gene X-ray repair cross-
complementing group 1 (XRCC1) Arg399Gln (rs25487), Arg194Trp (rs1799782), Arg280His …