Lipid-based vectors for therapeutic mRNA-based anti-cancer vaccines

ML Guevara, S Persano… - Current Pharmaceutical …, 2019 - ingentaconnect.com
Cancer vaccines have been widely explored as a key tool for effective cancer
immunotherapy. Despite a convincing rationale behind cancer vaccines, extensive past …

Considerations on the design of lipid-based mRNA vaccines against cancer

S Meulewaeter, Y Zhang, A Wadhwa, K Fox… - Journal of Molecular …, 2023 - Elsevier
Throughout the last decades, mRNA vaccines have been developed as a cancer
immunotherapeutic and the technology recently gained momentum during the COVID-19 …

Recent progress in mRNA cancer vaccines

R Yao, C Xie, X Xia - Human Vaccines & Immunotherapeutics, 2024 - Taylor & Francis
The research and development of messenger RNA (mRNA) cancer vaccines have gradually
overcome numerous challenges through the application of personalized cancer antigens …

Lipid nanoparticle-based mRNA vaccines in cancers: Current advances and future prospects

T Huang, L Peng, Y Han, D Wang, X He… - Frontiers in …, 2022 - frontiersin.org
Messenger RNA (mRNA) vaccines constitute an emerging therapeutic method with the
advantages of high safety and efficiency as well as easy synthesis; thus, they have been …

mRNA vaccines for cancer immunotherapy

YL Vishweshwaraiah, NV Dokholyan - Frontiers in immunology, 2022 - frontiersin.org
Immunotherapy has emerged as a breakthrough strategy in cancer treatment. mRNA
vaccines are an attractive and powerful immunotherapeutic platform against cancer because …

Recent advances in mRNA vaccine delivery

L Tan, X Sun - Nano Research, 2018 - Springer
In recent years, messenger RNA (mRNA) vaccines have been intensively studied in the
fields of cancer immunotherapy and infectious diseases because of their excellent efficacy …

mRNA vaccines and their delivery strategies: A journey from infectious diseases to cancer

RR Malla, M Srilatha, B Farran, GP Nagaraju - Molecular Therapy, 2024 - cell.com
mRNA vaccines have evolved as promising cancer therapies. These vaccines can encode
tumor-allied antigens, thus enabling personalized treatment approaches. They can also …

Lipid-based mRNA vaccine delivery systems

P Midoux, C Pichon - Expert review of vaccines, 2015 - Taylor & Francis
Synthetic mRNAs can become biopharmaceutics allowing vaccination against cancer,
bacterial and virus infections. Clinical trials with direct administration of synthetic mRNAs …

mRNA delivery systems for cancer immunotherapy: lipid nanoparticles and beyond

ME Senti, LG Del Valle, RM Schiffelers - Advanced Drug Delivery Reviews, 2024 - Elsevier
Abstract mRNA-based vaccines are emerging as a promising alternative to standard cancer
treatments and the conventional vaccines. Moreover, the FDA-approval of three nucleic acid …

mRNA Cancer vaccines: construction and boosting strategies

X Liu, P Huang, R Yang, H Deng - ACS nano, 2023 - ACS Publications
In late 2020, the US Food and Drug Administration (FDA) approved a lipid-based mRNA
vaccine for the prevention of COVID-19, which has pushed this field to be more closely …