The genetics of Mexico recapitulates Native American substructure and affects biomedical traits
Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-
wide variation from this region remain largely uncharacterized. We studied genomic …
wide variation from this region remain largely uncharacterized. We studied genomic …
Mexican Biobank advances population and medical genomics of diverse ancestries
Latin America continues to be severely underrepresented in genomics research, and fine-
scale genetic histories and complex trait architectures remain hidden owing to insufficient …
scale genetic histories and complex trait architectures remain hidden owing to insufficient …
Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture
We explored ancestry-related differences in the genetic architecture of whole-blood gene
expression using whole-genome and RNA sequencing data from 2,733 African Americans …
expression using whole-genome and RNA sequencing data from 2,733 African Americans …
Genotyping, sequencing and analysis of 140,000 adults from Mexico City
A Ziyatdinov, J Torres, J Alegre-Díaz, J Backman… - Nature, 2023 - nature.com
Abstract The Mexico City Prospective Study is a prospective cohort of more than 150,000
adults recruited two decades ago from the urban districts of Coyoacán and Iztapalapa in …
adults recruited two decades ago from the urban districts of Coyoacán and Iztapalapa in …
Analysis of genomic diversity in Mexican Mestizo populations to develop genomic medicine in Mexico
I Silva-Zolezzi, A Hidalgo-Miranda… - Proceedings of the …, 2009 - National Acad Sciences
Mexico is developing the basis for genomic medicine to improve healthcare of its population.
The extensive study of genetic diversity and linkage disequilibrium structure of different …
The extensive study of genetic diversity and linkage disequilibrium structure of different …
The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas
H García-Ortiz, F Barajas-Olmos… - Nature …, 2021 - nature.com
The genetic makeup of Indigenous populations inhabiting Mexico has been strongly
influenced by geography and demographic history. Here, we perform a genome-wide …
influenced by geography and demographic history. Here, we perform a genome-wide …
Genetic ancestry, admixture and health determinants in Latin America
Abstract Background Modern Latin American populations were formed via genetic admixture
among ancestral source populations from Africa, the Americas and Europe. We are …
among ancestral source populations from Africa, the Americas and Europe. We are …
Genomic insights into the ancestry and demographic history of South America
South America has a complex demographic history shaped by multiple migration and
admixture events in pre-and post-colonial times. Settled over 14,000 years ago by Native …
admixture events in pre-and post-colonial times. Settled over 14,000 years ago by Native …
Ancestral components of admixed genomes in a Mexican cohort
NA Johnson, MA Coram, MD Shriver, I Romieu… - PLoS …, 2011 - journals.plos.org
For most of the world, human genome structure at a population level is shaped by interplay
between ancient geographic isolation and more recent demographic shifts, factors that are …
between ancient geographic isolation and more recent demographic shifts, factors that are …
Genomic insights into the early peopling of the Caribbean
The Caribbean was one of the last regions of the Americas to be settled by humans, but
where they came from and how and when they reached the islands remain unclear. We …
where they came from and how and when they reached the islands remain unclear. We …
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