Type 2 diabetes mellitus (T2DM) is characterised by chronic low-grade inflammation,
recently referred to as 'metaflammation', a relevant factor contributing to the development of …

One of the concepts explaining the coincidence of obesity and type 2 diabetes (T2D) is the
metaflammation theory. This chronic, low-grade inflammatory state originating from …

Diabetes is a complex metabolic disorder affecting the glucose status of the human body.
Chronic hyperglycaemia related to diabetes is associated with end organ failure. The clinical …

Obesity-related sub-acute chronic inflammation has been associated with incident type 2
diabetes and atherosclerotic cardiovascular disease. Inflammation is increasingly …

The global prevalence of Type 2 diabetes mellitus and its associated complications are
growing rapidly. Although the role of hyperglycemia is well recognized in the …

Diabetes and hyperglycemia create a proinflammatory microenvironment that progresses to
microvascular complications such as nephropathy, retinopathy, and neuropathy. Diet …

The association between the metabolic syndrome and a pathological activation of the innate
immune system is now well established. Thus, defective insulin secretion and action are …

Ageing and age-related diseases share some basic mechanistic pillars that largely
converge on inflammation. During ageing, chronic, sterile, low-grade inflammation—called …

Diabetes mellitus is increasing at an alarming rate and has become a global challenge.
Insulin resistance in target tissues and a relative deficiency of insulin secretion from …

Type 2 diabetes mellitus (T2DM) is increasingly common worldwide. Related complications
account for increased morbidity and mortality, and enormous healthcare spending …