The pituitary gland functions as a relay between the hypothalamus and peripheral target
organs that regulate basic physiological functions, including growth, the stress response …

Defects in pituitary gland organogenesis are sometimes associated with congenital
anomalies that affect head development. Lesions in transcription factors and signaling …

Normal hypothalamopituitary development is closely related to that of the forebrain and is
dependent upon a complex genetic cascade of transcription factors and signaling molecules …

The pituitary gland has a relatively simple organization despite its central role as chef
d'orchestre of the endocrine system. Indeed, the glandular portion of the pituitary comprised …

Development of the pituitary gland and pituitary cell determination and specification depend
on the expression and interaction of signaling molecules and transcription factors in …

The mammalian anterior pituitary gland is a compound endocrine organ that regulates
reproductive development and fitness, growth, metabolic homeostasis, the response to …

Mouse models have been used to study various aspects of pituitary development, function
and disease. Transgenic or knockout technology has been applied to examine the …

The functions of the pituitary hormones have been relatively well studied; however,
understanding the regulation of their synthesis and release have been an ongoing subject of …

Many aspects of pituitary development have become better understood in the past two
decades. The signaling pathways regulating pituitary growth and shape have emerged, and …

The pituitary gland is a central endocrine organ regulating basic physiological functions,
including growth, the stress response, reproduction, metabolic homeostasis, and lactation …