The prevalence of osteoarthritis (OA) and the burden associated with the disease are
steadily increasing worldwide, representing a major public health challenge for the coming …

Introduction: Osteoarthritis (OA) is the leading cause of pain, loss of function, and disability
among elderly, with the knee the most affected joint. It is a heterogeneous condition …

Osteoarthritis (OA) is the most common joint disease and a leading cause for impaired
function and disability with significant treatment costs and socio-economic burden. Despite …

Osteoarthritis (OA) is the leading cause of function loss and disability among the elderly, with
significant burden on the individual and society. It is a severe disease for its high disability …

Osteoarthritis (OA) is a prevalent and disabling condition for which few safe and effective
therapeutic options are available. Current approaches are largely palliative and in an effort …

Osteoarthritis (OA) is a prevalent and severely debilitating disease with an unmet medical
need. In order to alleviate OA symptoms or prevent structural progression of OA, new drugs …

OBJECTIVE: The purpose of this article is to review the current status of drug development
as it relates to both molecular targets and clinical trials for osteoarthritis (OA). METHODS: A …

New treatment options are needed for osteoarthritis (OA) to slow down the structural
progression of the disease; current therapies mostly target pain and function with minimal …

Introduction: Osteoarthritis (OA), the most prevalent form of joint disease, affects as much as
13% of the world's population. In the USA, it is the leading cause of disability in people over …

Osteoarthritis (OA) is a disease of the joints that affects several million individuals worldwide.
This disease, which involves mainly the diarthrodial joints, is chronic and develops slowly …