[PDF][PDF] Animal models of obesity.

J Speakman, C Hambly, S Mitchell, E Krol - Obesity Reviews, 2007 - researchgate.net
Background Obesity stems from a prolonged imbalance between the levels of energy intake
and expenditure, with the resultant surplus being stored as body lipids. Our understanding of …

The contribution of animal models to the study of obesity

J Speakman, C Hambly, S Mitchell… - Laboratory animals, 2008 - journals.sagepub.com
Obesity results from prolonged imbalance of energy intake and energy expenditure. Animal
models have provided a fundamental contribution to the historical development of …

Translational value of animal models of obesity—Focus on dogs and cats

M Osto, TA Lutz - European journal of pharmacology, 2015 - Elsevier
A prolonged imbalance between a relative increase in energy intake over a decrease in
energy expenditure results in the development of obesity; extended periods of a positive …

Relevance of animal models to human eating disorders and obesity

RC Casper, EL Sullivan, L Tecott - Psychopharmacology, 2008 - Springer
Background and rationale This review addresses the role animal models play in contributing
to our knowledge about the eating disorders anorexia nervosa (AN) and bulimia nervosa …

Lessons from animal models of obesity

DA York - Endocrinology and metabolism clinics of North America, 1996 - Elsevier
The animal models that have been used for the study of obesity have been either of
spontaneous origin or the result of experimental manipulation of the environment or the …

Diet‐induced rodent models of obesity‐related metabolic disorders—a guide to a translational perspective

I Preguiça, A Alves, S Nunes, R Fernandes… - Obesity …, 2020 - Wiley Online Library
Diet is a critical element determining human health and diseases, and unbalanced food
habits are major risk factors for the development of obesity and related metabolic disorders …

Murine models of obesity

T Martins, C Castro-Ribeiro, S Lemos, T Ferreira… - Obesities, 2022 - mdpi.com
Obesity, classified as an epidemic by the WHO, is a disease that continues to grow
worldwide. Obesity results from abnormal or excessive accumulation of fat and usually leads …

Overview of animal models of obesity

TA Lutz, SC Woods - Current protocols in pharmacology, 2012 - Wiley Online Library
The focus of this overview is on the animal models of obesity most commonly utilized in
research. The models include monogenic models in the leptin pathway, polygenic diet …

Use of high-fat diets to study rodent obesity as a model of human obesity

JR Speakman - International journal of obesity, 2019 - nature.com
The main focus of the International Journal of Obesity (IJO) is to better understand human
obesity. Many scientists use rodents as convenient models to dissect aspects of physiology …

Diet-induced obesity in animal models: points to consider and influence on metabolic markers

M de Moura e Dias, SA Dos Reis… - Diabetology & Metabolic …, 2021 - Springer
Overweight and obesity are a worldwide public health problem. Obesity prevalence has
increased considerably, which indicates the need for more studies to better understand …