Immunopathogenesis of genital Chlamydia infection: insights from mouse models

J Dockterman, J Coers - Pathogens and Disease, 2021 - academic.oup.com
Chlamydiae are pathogenic intracellular bacteria that cause a wide variety of diseases
throughout the globe, affecting the eye, lung, coronary arteries and female genital tract …

Immunopathogenesis of chlamydial infections

AK Murthy, W Li, KH Ramsey - Biology of Chlamydia, 2018 - Springer
Chlamydial infections lead to a number of clinically relevant diseases and induce significant
morbidity in human populations. It is generally understood that certain components of the …

Chlamydia‐infected macrophages are resistant to azithromycin treatment and are associated with chronic oviduct inflammation and hydrosalpinx development

MCG Harvie, AJ Carey, CW Armitage… - Immunology and cell …, 2019 - Wiley Online Library
Chlamydia infection remains the leading sexually‐transmitted bacterial infection worldwide,
causing damaging sequelae such as tubal scarring, infertility and ectopic pregnancy. As …

The mouse model of Chlamydia genital tract infection: a review of infection, disease, immunity and vaccine development

CP O'Meara, DW Andrew… - Current molecular …, 2014 - ingentaconnect.com
Chlamydia trachomatis is the most common sexually transmitted bacterial infection
worldwide. The impact of this pathogen on human reproduction has intensified research …

Innate immunity is sufficient for the clearance of Chlamydia trachomatis from the female mouse genital tract

GL Sturdevant, HD Caldwell - Pathogens and disease, 2014 - academic.oup.com
Chlamydia muridarum and Chlamydia trachomatis, mouse and human strains, respectively,
have been used to study immunity in a murine model of female genital tract infection …

Immunity to murine chlamydial genital infection

RP Morrison, HD Caldwell - Infection and immunity, 2002 - Am Soc Microbiol
Chlamydia trachomatis sexually transmitted infections cause considerable morbidity and
socioeconomic burden worldwide, despite significant advances in our understanding of the …

Chlamydia trachomatis: Protective Adaptive Responses and Prospects for a Vaccine

TB Poston, T Darville - Biology of Chlamydia, 2018 - Springer
Chlamydia trachomatis is the most common cause of sexually transmitted bacterial infection
globally. These infections translate to a significant public health burden, particularly …

A genital infection-attenuated Chlamydia muridarum mutant infects the gastrointestinal tract and protects against genital tract challenge

SG Morrison, AM Giebel, E Toh, A Banerjee… - Mbio, 2020 - Am Soc Microbiol
Chlamydia spp. productively infect mucosal epithelial cells of multiple anatomical sites,
including the conjunctiva, lungs, gastrointestinal (GI) tract, and urogenital tract. We, and …

[HTML][HTML] Chlamydia trachomatis: Cell biology, immunology and vaccination

SM Murray, PF McKay - Vaccine, 2021 - Elsevier
Chlamydia trachomatis is the causative agent of a highly prevalent sexually transmitted
bacterial disease and is associated with a number of severe disease complications. Current …

Protective immunity to chlamydial genital infection: evidence from animal studies

RG Rank, JA Whittum-Hudson - The Journal of infectious …, 2010 - academic.oup.com
In all animal models for chlamydial infection, there is strong evidence for immunity to
reinfection; however, immunity is only complete (ie, preventing infection) in the short term. In …