Interim report from a 2-year double-blind rct testing fermented papaya preparation on immune enhancement, endothelial health and qol in elderly adults

A Lorenzetti, M Osato, F He, C Aperio… - Functional Foods in …, 2023 - idus.us.es
profile, and endothelial cell dysfunction. Indeed, increased generation of free radicals as
well as immunosenescence are hallmarks of the aging process and age-related diseases. In …

Neutrophil-lymphocyte ratio and update conclusions from a 2-year double-blind rct testing fermented papaya preparation in healthy middle-aged/elderly subjects

A Lorenzetti, A Ayala Gómez, F He, C Aperio… - … Food Science, 4 (1), 29 …, 2024 - idus.us.es
Background: T his study represents the second part of a 2-year interventional study in
middle-aged/elderly healthy subjects treated either with an antioxidant supplementation …

Effects of Fermented Papaya Preparation (FPP) on Safety Outcomes in Older Adults–A Short Report of a Placebo-Controlled Clinical Trial

RT Mankowski, C Leeuwenburgh, TM Manini… - The Journal of Frailty & …, 2018 - Springer
Abstract Fermented Papaya Preparation (FPP®) has shown antioxidative and anti-
inflammatory effects in preclinical and clinical aging studies. However, clinical trials are …

Beneficial Effects of Fermented Papaya Preparation (FPP®) Supplementation on Redox Balance and Aging in a Mouse Model

M Logozzi, R Di Raimo, D Mizzoni, M Andreotti… - Antioxidants, 2020 - mdpi.com
In recent decades much attention has been paid to how dietary antioxidants may positively
affect the human health, including the beneficial effects of fermented foods and beverages …

Applications and bioefficacy of the functional food supplement fermented papaya preparation

OI Aruoma, Y Hayashi, F Marotta, P Mantello… - Toxicology, 2010 - Elsevier
Fermented papaya preparation (FPP)(a product of yeast fermentation of Carica papaya
Linn) is a food supplement. Studies in chronic and degenerative disease conditions (such as …

Fermented papaya preparation restores age-related reductions in peripheral blood mononuclear cell cytolytic activity in tube-fed patients

Y Fujita, H Tsuno, J Nakayama - PLoS One, 2017 - journals.plos.org
Tube-fed elderly patients are generally supplied with the same type of nutrition over long
periods, resulting in an increased risk for micronutrient deficiencies. Dietary polyphenols …

[HTML][HTML] A 2-year double-blind RCT follow-up study with fermented papaya preparation (FPP) modulating key markers in middle-age subjects with clustered …

F Marotta, M Marcellino, U Solimene… - Clinical …, 2017 - ncbi.nlm.nih.gov
In recent years a number of studies have reported the significant relationship between
metabolic syndrome and neurodegenerative disease. There is accumulating evidence that …

Carica papaya increases regulatory T cells and reduces IFN‐γ+CD4+ T cells in healthy human subjects

M Abdullah, PS Chai, CY Loh… - Molecular nutrition & …, 2011 - Wiley Online Library
Fruit and vegetables have therapeutic potential as they dampen inflammation, have no
known side‐effects and as whole foods have prospective additive and synergistic benefits …

Discovering the health promoting potential of fermented papaya preparation—its future perspectives for the dietary management of oxidative stress during diabetes

J Somanah, M Putteeraj, OI Aruoma, T Bahorun - Fermentation, 2018 - mdpi.com
The simplistic morphological characteristics of Carica papaya fruit or “pawpaw” should not
be the cause for underestimating its potential as a nutraceutical. The market for papaya has …

Does oral supplementation of a fermented papaya preparation correct respiratory burst function of innate immune cells in type 2 diabetes mellitus patients?

R Dickerson, J Banerjee, A Rauckhorst, DR Pfeiffer… - 2015 - liebertpub.com
Fermented papaya preparation (FPP) is a nutritional supplement reported to act as an
antioxidant by scavenging reactive oxygen species (ROS) and removing “bad ROS,” while …