Ischemic stroke (IS) is a detrimental neurological disease with limited treatments options. It
has been challenging to define the roles of brain cell subsets in IS onset and progression …

Background The transient middle cerebral artery occlusion (tMCAO) model is used for
studying the molecular mechanisms of ischemic damage and neuroprotection. Numerous …

Background Damage in the ischemic core and penumbra after stroke affects patient
prognosis. Microglia immediately respond to ischemic insult and initiate immune …

Stroke has been the leading cause of adult morbidity and mortality over the past several
years. After an ischemic stroke attack, many dormant or reversibly injured brain cells exist in …

Background. This study is aimed at investigating the changes in relevant pathways and the
differential expression of related gene expression after ischemic stroke (IS) at the single‐cell …

Cerebrovascular injuries can cause severe edema and inflammation that adversely affect
human health. Here, we observed that recanalization after successful endovascular …

Objective Bridging the gap between experimental stroke and patients by ischemic blood
probing during the hyperacute stage of vascular occlusion is crucial to assess the role of …

Background Ischemic stroke (IS) was a significant public health concern and long-chain
noncoding RNAs (lncRNAs) were gaining particular importance in stroke biology, however …

Ischemic stroke accounts for the majority of stroke cases and constitutes a major cause of
death and disability in the industrialized world. Inflammation has been reported to constitute …

Astrocytes support normal brain function, but may also contribute to neurodegeneration
when they become reactive under pathological conditions such as stroke. However, the …