Recurrent deletions and duplications at chromosomal region 16p11. 2 are variably
associated with speech delay, autism spectrum disorder, developmental delay …

Abstract 16p11. 2 deletion is one of the most common gene copy variations that increases
the susceptibility to autism and other neurodevelopmental disorders. This syndrome leads to …

Paternally and maternally inherited deletions and duplications of human chromosome
15q11‐13 are relatively common in the human population. Furthermore, duplications in the …

Mouse models offer indispensable heuristic tools for studying genetic and environmental
causes of neuropsychiatric disorders, including autism. Development of useful animal …

Sleep disturbances and hyperactivity are prevalent in several neurodevelopmental
disorders, including autism spectrum disorders (ASDs) and attention deficit‐hyperactivity …

A deletion on human chromosome 16p11. 2 is associated with autism spectrum disorders.
We deleted the syntenic region on mouse chromosome 7F3. MRI and high-throughput …

Background Microdeletion of the human 16p11. 2 gene locus confers risk for autism
spectrum disorders and intellectual disability. How 16p11. 2 deletion is linked to these …

Abstract The human 16p11. 2 gene locus is a hot spot for copy number variations, which
predispose carriers to a range of neuropsychiatric phenotypes. Microduplications of 16p11 …

Background Deletion of the recurrent~ 600 kb BP4-BP5 chromosomal region 16p11. 2 has
been associated with a wide range of neurodevelopmental outcomes. Methods To clarify the …

Chromosome 16p11. 2 deletions and duplications are among the most frequent genetic
etiologies of autism spectrum disorder (ASD) and other neurodevelopmental disorders, but …