Left ventricular (LV) remodeling (ie, enlargement and functional deterioration occurring over
time) is among the main mechanisms of progression in heart failure (HF). LV dilatation and …

Recent clinical investigations have provided new insights into physiologic alterations taking
place as heart failure progresses. As a result, new end points may be more relevant to …

Cardiac remodeling is generally accepted as a determinant of the clinical course of heart
failure (HF). Defined as genome expression resulting in molecular, cellular and interstitial …

Ventricular remodeling refers to changes in left ventricular (LV) geometry, mass, and volume
in response to myocardial injury or alterations in load. The extent of LV dilatation or …

Adverse remodeling involves a complicated process of structural and functional changes in
the left ventricle (LV). LV remodeling is progressive and, if left unchecked, culminates in …

This review briefly highlights the major mechanisms of left ventricular (LV) remodeling
following myocardial infarction in heart failure and presents novel strategies to limit infarct …

Left ventricular (LV) remodeling has an important role in the progression of cardiovascular
disease. An understanding of the process of LV remodeling has led to greater knowledge of …

Background: A major advance in understanding the pathophysiology of the heart failure
syndrome has been an understanding of the process of left ventricular (LV) remodeling. After …

Objectives: The objective of this study was to test the hypothesis that the severity of left
ventricular remodeling predicts the response to treatment and outcomes in chronic heart …

As the number of treatments for heart failure (HF) increases and mortality decreases in the
setting of clinical trials, the size of the study population required to demonstrate an …