[HTML][HTML] Mitochondrial dysfunction in diabetic kidney disease
JM Forbes, DR Thorburn - Nature Reviews Nephrology, 2018 - nature.com
Globally, diabetes is the leading cause of chronic kidney disease and end-stage renal
disease, which are major risk factors for cardiovascular disease and death. Despite this …
disease, which are major risk factors for cardiovascular disease and death. Despite this …
Mitochondrial dysfunction and signaling in diabetic kidney disease: oxidative stress and beyond
The kidneys are highly metabolic organs that produce vast quantities of adenosine
triphosphate via oxidative phosphorylation and, as such, contain many mitochondria …
triphosphate via oxidative phosphorylation and, as such, contain many mitochondria …
Mitochondria in diabetic kidney disease
AA Ahmad, SO Draves, M Rosca - Cells, 2021 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of end stage renal disease (ESRD) in
the USA. The pathogenesis of DKD is multifactorial and involves activation of multiple …
the USA. The pathogenesis of DKD is multifactorial and involves activation of multiple …
Mitochondrial dysfunction in diabetic kidney disease
PZ Wei, CC Szeto - Clinica Chimica Acta, 2019 - Elsevier
Although diabetic kidney disease (DKD) is the most common cause of end-stage kidney
disease worldwide, the pathogenic mechanisms are poorly understood. There is increasing …
disease worldwide, the pathogenic mechanisms are poorly understood. There is increasing …
The role of mitochondria in diabetic kidney disease
S Hallan, K Sharma - Current Diabetes Reports, 2016 - Springer
Despite major improvements in the treatment of patients with diabetes mellitus, many
patients still suffer from progressive diabetic kidney disease. More research is needed to …
patients still suffer from progressive diabetic kidney disease. More research is needed to …
[HTML][HTML] The hallmarks of mitochondrial dysfunction in chronic kidney disease
DL Galvan, NH Green, FR Danesh - Kidney international, 2017 - Elsevier
Recent advances have led to a greater appreciation of how mitochondrial dysfunction
contributes to diverse acute and chronic pathologies. Indeed, mitochondria have received …
contributes to diverse acute and chronic pathologies. Indeed, mitochondria have received …
Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?
GC Higgins, MT Coughlan - British journal of pharmacology, 2014 - Wiley Online Library
Diabetic nephropathy (DN) is a progressive microvascular complication arising from
diabetes. Within the kidney, the glomeruli, tubules, vessels and interstitium are disrupted …
diabetes. Within the kidney, the glomeruli, tubules, vessels and interstitium are disrupted …
[HTML][HTML] Mitochondrial energetics in the kidney
P Bhargava, RG Schnellmann - Nature Reviews Nephrology, 2017 - nature.com
The kidney requires a large number of mitochondria to remove waste from the blood and
regulate fluid and electrolyte balance. Mitochondria provide the energy to drive these …
regulate fluid and electrolyte balance. Mitochondria provide the energy to drive these …
Pharmacological targeting of mitochondria in diabetic kidney disease
KH Cleveland, RG Schnellmann - Pharmacological Reviews, 2023 - ASPET
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD) in
the United States and many other countries. DKD occurs through a variety of pathogenic …
the United States and many other countries. DKD occurs through a variety of pathogenic …
Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes
MT Coughlan, TV Nguyen, SA Penfold… - Clinical …, 2016 - portlandpress.com
Oxidative phosphorylation (OXPHOS) drives ATP production by mitochondria, which are
dynamic organelles, constantly fusing and dividing to maintain kidney homoeostasis. In …
dynamic organelles, constantly fusing and dividing to maintain kidney homoeostasis. In …