Glioblastoma (GBM) is the most common primary malignant brain tumor in adults with an
extremely poor prognosis. There is a dire need to develop effective therapeutics to …

Simple Summary Glioblastoma is a devastating malignancy that has continued to prove
resistant to a variety of therapeutics. No new systemic therapy has been approved for use …

Simple Summary Introducing novel and effective treatments against glioblastoma (GBM)
remains an arduous journey as reflected in the negative outcome of most clinical trials. The …

Glioblastoma (GBM) is one of the most common, deadly, and difficult-to-treat adult brain
tumors. Surgical removal of the tumor, followed by radiotherapy (RT) and temozolomide …

Malignant gliomas are still extremely difficult to treat because complete surgical resection is
biologically not feasible due to the invasive nature of these diseases and the proximity of …

Glioblastoma multiforme is the most common, aggressive and lethal type of brain tumor. It is
a stage IV cancer disease with a poor prognosis, as the current therapeutic options (surgery …

Abstract Background Glioblastoma Multiforme is the deadliest type of brain tumor and is
characterized by very poor prognosis with a limited overall survival. Current optimal …

Glioblastoma multiforme (GBM) is an extremely malignant type of brain cancer which
originates from astrocytes or their precursors. Glioblastoma multiforme cells share some …

Glioblastoma (GBM) is the most common and lethal primary brain tumor which is highly
resistant to conventional radiotherapy and chemotherapy, and cannot be effectively …

Glioblastoma multiforme, because of its invasive nature, can be considered a disease of the
entire brain. Despite recent advances in surgery, radiotherapy and chemotherapy, current …