Exploring m6A‐RNA methylation as a potential therapeutic strategy for acute lung injury and acute respiratory distress syndrome
Abstract N6‐methyladenosine (m6A) is the most common methylation modification in
mammalian messenger RNA (mRNA) and noncoding RNAs. m6A modification plays a role …
mammalian messenger RNA (mRNA) and noncoding RNAs. m6A modification plays a role …
The effect of N6-methyladenosine (m6A) factors on the development of acute respiratory distress syndrome in the mouse model
L Fei, G Sun, J Sun, D Wu - Bioengineered, 2022 - Taylor & Francis
Acute respiratory distress syndrome (ARDS) can cause loss of alveolar-capillary membrane
integrity and life-threatening immune responses. The underlying molecular mechanisms of …
integrity and life-threatening immune responses. The underlying molecular mechanisms of …
[HTML][HTML] METTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner
F Cao, G Chen, Y Xu, X Wang, X Tang, W Zhang… - Cell Death & …, 2024 - nature.com
Acute lung injury (ALI) as well as its more severe form, acute respiratory distress syndrome
(ARDS), frequently leads to an uncontrolled inflammatory response. N6-methyladenosine …
(ARDS), frequently leads to an uncontrolled inflammatory response. N6-methyladenosine …
Emerging role of N6-methyladenosine RNA methylation in lung diseases
L Xu, L Zhou, C Yan, L Li - Experimental Biology and …, 2022 - journals.sagepub.com
In recent years, with the increase of air pollution, smoking, aging, and respiratory infection,
the incidence rate and mortality of lung diseases are increasing annually, which has …
the incidence rate and mortality of lung diseases are increasing annually, which has …
[HTML][HTML] N6-methyladenosine (m6A) methylation in ischemia–reperfusion injury
W Yao, X Han, M Ge, C Chen, X Xiao, H Li, Z Hei - Cell death & disease, 2020 - nature.com
Abstract Ischemia–reperfusion (I/R) injury is common during surgery and often results in
organ dysfunction. The mechanisms of I/R injury are complex, diverse, and not well …
organ dysfunction. The mechanisms of I/R injury are complex, diverse, and not well …
[HTML][HTML] Comprehensive analysis of m6A modification in lipopolysaccharide-induced acute lung injury in mice
C Xu, C Song, W Wang, B Liu, G Li, T Fu, B Hao, N Li… - Molecular …, 2024 - Springer
Abstract Background N6-Methyladenosine (m6A) methylation is the most prevalent post-
transcriptional modification in mRNA, and plays significant roles in various diseases …
transcriptional modification in mRNA, and plays significant roles in various diseases …
[HTML][HTML] N6-methyladenosine modification: Regulatory mechanisms and therapeutic potential in sepsis
W Wang, H Wang, T Sun - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection and is characterized by multiple biological and clinical features. N 6 …
infection and is characterized by multiple biological and clinical features. N 6 …
Immune Infiltration and N (6)‐Methyladenosine ncRNA Isoform Detection in Acute Lung Injury
C Gu, C Li, W Wang, W Yan, Y Yao, M Shi… - Journal of …, 2022 - Wiley Online Library
Acute lung injury (ALI) is a severe form of sepsis that is associated with a high rate of
morbidity and death in critically ill individuals. The emergence of ALI is the result of several …
morbidity and death in critically ill individuals. The emergence of ALI is the result of several …
N6-methyladenosine reader YTH N6-methyladenosine RNA binding protein 3 or insulin like growth factor 2 mRNA binding protein 2 knockdown protects human …
K Xiao, P Liu, P Yan, Y Liu, L Song, Y Liu, L Xie - Bioengineered, 2022 - Taylor & Francis
Lung ischemia/reperfusion (I/R) injury (LIRI) is a common complication after lung
transplantation, embolism, and trauma. N6-methyladenosine (m6A) methylation modification …
transplantation, embolism, and trauma. N6-methyladenosine (m6A) methylation modification …
[HTML][HTML] Tamping Down the Fire: Taming Pyroptosis through RNA Methylation in Acute Lung Injury
KWD Shin, RB Hamanaka - American Journal of Respiratory Cell …, 2024 - atsjournals.org
The recent Coronavirus Disease 19 (COVID-19) pandemic has highlighted the need for a
greater understanding of the pathogenesis of Acute Respiratory Distress Syndrome (ARDS) …
greater understanding of the pathogenesis of Acute Respiratory Distress Syndrome (ARDS) …