Exercise mitigates age-related metabolic diseases by improving mitochondrial dysfunction
D Jia, Z Tian, R Wang - Ageing Research Reviews, 2023 - Elsevier
The benefits of regular physical activity are related to delaying and reversing the onset of
ageing and age-related disorders, including cardiomyopathy, neurodegenerative diseases …
ageing and age-related disorders, including cardiomyopathy, neurodegenerative diseases …
Exercise and mitochondrial health
JM Memme, AT Erlich, G Phukan… - The Journal of …, 2021 - Wiley Online Library
Mitochondrial health is an important mediator of cellular function across a range of tissues,
and as a result contributes to whole‐body vitality in health and disease. Our understanding …
and as a result contributes to whole‐body vitality in health and disease. Our understanding …
Exercise improves mitochondrial and redox-regulated stress responses in the elderly: better late than never!
Ageing is associated with several physiological declines to both the cardiovascular (eg
reduced aerobic capacity) and musculoskeletal system (muscle function and mass). Ageing …
reduced aerobic capacity) and musculoskeletal system (muscle function and mass). Ageing …
Mitochondrial and metabolic dysfunction in ageing and age-related diseases
Organismal ageing is accompanied by progressive loss of cellular function and systemic
deterioration of multiple tissues, leading to impaired function and increased vulnerability to …
deterioration of multiple tissues, leading to impaired function and increased vulnerability to …
Beneficial effects of exercise on age‐related mitochondrial dysfunction and oxidative stress in skeletal muscle
AM Joseph, PJ Adhihetty… - The Journal of …, 2016 - Wiley Online Library
Mitochondria are negatively affected by ageing leading to their inability to adapt to higher
levels of oxidative stress and this ultimately contributes to the systemic loss of muscle mass …
levels of oxidative stress and this ultimately contributes to the systemic loss of muscle mass …
Mitochondria and aging—The role of exercise as a countermeasure
MI Nilsson, MA Tarnopolsky - Biology, 2019 - mdpi.com
Mitochondria orchestrate the life and death of most eukaryotic cells by virtue of their ability to
supply adenosine triphosphate from aerobic respiration for growth, development, and …
supply adenosine triphosphate from aerobic respiration for growth, development, and …
[HTML][HTML] Mitochondrial redox metabolism in aging: Effect of exercise interventions
H Bo, N Jiang, LL Ji, Y Zhang - Journal of Sport and Health Science, 2013 - Elsevier
Mitochondrial redox metabolism has long been recognized as being central to the effects of
aging and the development of age-related pathologies in the major oxidative organs …
aging and the development of age-related pathologies in the major oxidative organs …
Targeting mitochondria to counteract age-related cellular dysfunction
CT Madreiter-Sokolowski, AA Sokolowski… - Genes, 2018 - mdpi.com
Senescence is related to the loss of cellular homeostasis and functions, which leads to a
progressive decline in physiological ability and to aging-associated diseases. Since …
progressive decline in physiological ability and to aging-associated diseases. Since …
Mitochondrial ROS and aging: understanding exercise as a preventive tool
Sarcopenia, which is characterized by reduction in muscle mass and strength, contributes to
several age-related conditions, including insulin resistance and frailty. Despite the …
several age-related conditions, including insulin resistance and frailty. Despite the …
The emerging role of skeletal muscle mitochondrial dynamics in exercise and ageing
RA Casuso, JR Huertas - Ageing research reviews, 2020 - Elsevier
Mitochondria are the hub for energy production within living cells. They can undergo
morphological changes in response to nutrient availability and cellular stress. Here, we …
morphological changes in response to nutrient availability and cellular stress. Here, we …