The benefits of regular physical activity are related to delaying and reversing the onset of
ageing and age-related disorders, including cardiomyopathy, neurodegenerative diseases …

Mitochondrial health is an important mediator of cellular function across a range of tissues,
and as a result contributes to whole‐body vitality in health and disease. Our understanding …

Ageing is associated with several physiological declines to both the cardiovascular (eg
reduced aerobic capacity) and musculoskeletal system (muscle function and mass). Ageing …

Organismal ageing is accompanied by progressive loss of cellular function and systemic
deterioration of multiple tissues, leading to impaired function and increased vulnerability to …

Mitochondria are negatively affected by ageing leading to their inability to adapt to higher
levels of oxidative stress and this ultimately contributes to the systemic loss of muscle mass …

Mitochondria orchestrate the life and death of most eukaryotic cells by virtue of their ability to
supply adenosine triphosphate from aerobic respiration for growth, development, and …

Mitochondrial redox metabolism has long been recognized as being central to the effects of
aging and the development of age-related pathologies in the major oxidative organs …

Senescence is related to the loss of cellular homeostasis and functions, which leads to a
progressive decline in physiological ability and to aging-associated diseases. Since …

Sarcopenia, which is characterized by reduction in muscle mass and strength, contributes to
several age-related conditions, including insulin resistance and frailty. Despite the …

Mitochondria are the hub for energy production within living cells. They can undergo
morphological changes in response to nutrient availability and cellular stress. Here, we …