Closing the loop for patients with Parkinson disease: where are we?

H Teymourian, F Tehrani, K Longardner… - Nature Reviews …, 2022 - nature.com
Although levodopa remains the most efficacious symptomatic therapy for Parkinson disease
(PD), management of levodopa treatment during the advanced stages of the disease is …

[HTML][HTML] Toward precision medicine in Parkinson's disease

LL Bu, K Yang, WX Xiong, FT Liu… - Annals of …, 2016 - ncbi.nlm.nih.gov
Precision medicine refers to an innovative approach selected for disease prevention and
health promotion according to the individual characteristics of each patient. The goal of …

[HTML][HTML] Large-scale wearable sensor deployment in Parkinson's patients: the Parkinson@ home study protocol

ALS de Lima, T Hahn, NM de Vries… - JMIR research …, 2016 - researchprotocols.org
Background: Long-term management of Parkinson's disease does not reach its full potential
because we lack knowledge about individual variations in clinical presentation and disease …

Improving the delivery of levodopa in Parkinson's disease: A review of approved and emerging therapies

D Urso, KR Chaudhuri, MA Qamar, P Jenner - CNS drugs, 2020 - Springer
Levodopa is the most effective drug for the treatment of Parkinson's disease, but its use as
an oral medication is complicated by its erratic absorption, extensive metabolism and short …

[HTML][HTML] Deep learning and wearable sensors for the diagnosis and monitoring of Parkinson's disease: a systematic review

L Sigcha, L Borzì, F Amato, I Rechichi… - Expert Systems with …, 2023 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder that produces both motor and non-
motor complications, degrading the quality of life of PD patients. Over the past two decades …

[HTML][HTML] Accelerometer data collected with a minimum set of wearable sensors from subjects with Parkinson's disease

JF Daneault, G Vergara-Diaz, F Parisi, C Admati… - Scientific Data, 2021 - nature.com
Parkinson's disease (PD) is a neurodegenerative disorder associated with motor and non-
motor symptoms. Current treatments primarily focus on managing motor symptom severity …

[HTML][HTML] Newly approved and investigational drugs for motor symptom control in Parkinson's disease

DG Di Luca, NGD Reyes, SH Fox - Drugs, 2022 - Springer
Motor symptoms are a core feature of Parkinson's disease (PD) and cause a significant
burden on patients' quality of life. Oral levodopa is still the most effective treatment, however …

[HTML][HTML] How wearable sensors can support Parkinson's disease diagnosis and treatment: a systematic review

E Rovini, C Maremmani, F Cavallo - Frontiers in neuroscience, 2017 - frontiersin.org
Background: Parkinson's disease (PD) is a common and disabling pathology that is
characterized by both motor and non-motor symptoms and affects millions of people …

Oral and infusion levodopa-based strategies for managing motor complications in patients with Parkinson's disease

A Antonini, K Ray Chaudhuri, P Martinez-Martin… - CNS drugs, 2010 - Springer
Levodopa is the most effective treatment for Parkinson's disease (PD) signs and symptoms,
and patients invariably will require it during the course of the disease. It also provides …

[HTML][HTML] Overview on wearable sensors for the management of Parkinson's disease

C Moreau, T Rouaud, D Grabli, I Benatru… - npj Parkinson's …, 2023 - nature.com
Parkinson's disease (PD) is affecting about 1.2 million patients in Europe with a prevalence
that is expected to have an exponential increment, in the next decades. This epidemiological …