Emerging role of HuR in inflammatory response in kidney diseases

J Shang, Z Zhao - Acta Biochimica et Biophysica Sinica, 2017 - academic.oup.com
Human antigen R (HuR) is a member of the embryonic lethal abnormal vision (ELAV) family
which can bind to the A/U rich elements in 3'un-translated region of mRNA and regulate …

Human antigen R: A potential therapeutic target for liver diseases

R Liu, K Wu, Y Li, R Sun, X Li - Pharmacological Research, 2020 - Elsevier
Human antigen R (HuR), also known as HuA and embryonic lethal abnormal vision-like 1
(ELAVL1), is a ubiquitously expressed RNA binding protein and functions as an RNA …

Down-regulation of HuR inhibits pathological angiogenesis in oxygen-induced retinopathy

XM Huang, Q Liu, ZY Xu, XH Yang, F Xiao… - Experimental Eye …, 2023 - Elsevier
HuR (also known as ELAV1), a ubiquitous RNA-binding protein, is implicated in the
pathogenesis of diverse diseases via the mechanism of post-transcriptional regulation …

HuR regulates the expression of stress-sensitive genes and mediates inflammatory response in human umbilical vein endothelial cells

WJ Rhee, CW Ni, Z Zheng, K Chang… - Proceedings of the …, 2010 - National Acad Sciences
An important aspect of vascular biology is the identification of regulators of stress-sensitive
genes that play critical roles in mediating inflammatory response. Here, we show that …

Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis

S Liu, Z Huang, A Tang, X Wu, J Aube, L Xu… - Clinical …, 2020 - portlandpress.com
Recent identification of an RNA-binding protein (HuR) that regulates mRNA turnover and
translation of numerous transcripts via binding to an ARE in their 3′-UTR involved in …

Expression of the ELAV-like protein HuR in the cytoplasm is associated with endometrial carcinoma progression

D Wang, M Wang, C Hu, T Shuang, Y Zhou, X Yan - Tumor Biology, 2014 - Springer
Human antigen R (HuR) is an mRNA-binding factor that belongs to the embryonic lethal
abnormal vision/Hu protein family which may function as a tumor maintenance gene in a …

[HTML][HTML] Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis

J Wang, Y Guo, H Chu, Y Guan, J Bi… - International journal of …, 2013 - mdpi.com
The human embryonic lethal abnormal vision-like protein, HuR, is a member of the Hu family
of RNA-binding proteins. Over the past decade, this ubiquitously expressed protein has …

Multiple functions of HuR in urinary tumors

F Zhang, Z Cai, H Lv, W Li, M Liang, X Wei… - Journal of Cancer …, 2019 - Springer
Purpose Human embryonic lethal abnormal visual-like protein, HuR, belongs to a member
of the Hu family of RNA-binding protein and plays a critical role in urinary tumors. The …

Cytoskeleton-dependent transport as a potential target for interfering with post-transcriptional HuR mRNA regulons

W Eberhardt, A Badawi, A Biyanee… - Frontiers in …, 2016 - frontiersin.org
The ubiquitous mRNA binding protein human antigen R (HuR), a member of the embryonal
lethal abnormal vision protein family has a critical impact on the post-transcriptional control …

Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis

S Liu, X Jiang, X Cui, J Wang, S Liu, H Li, J Yang… - Cell Death & …, 2021 - nature.com
Human antigen R (HuR) is a widespread RNA-binding protein involved in homeostatic
regulation and pathological processes in many diseases. Atherosclerosis is the leading …