Small interfering RNA (siRNA)-based gene silencing technology has demonstrated
significant potential for treating brain-associated diseases. However, effective and safe …

Neurodegenerative disorders (NDs) lead to the progressive degeneration of the structural
and physiological functions of the central and peripheral nervous systems, resulting in …

The ability to specifically silence genes using RNA interference (RNAi) has wide therapeutic
applications for the treatment of disease or the augmentation of tissue formation. RNAi is the …

Small interfering RNA (siRNA) has proved to be a powerful tool for target-specific gene
silencing via RNA interference (RNAi). Its ability to control targeted gene expression gives …

Gene therapy is a promising tool for the treatment of human diseases that cannot be cured
by rational therapies. The major limitation for the use of small interfering RNA (siRNA), both …

Gene silencing by RNA interference represents a promising therapeutic approach. The
development of carriers, eg, polymers, lipids, peptides, antibodies, aptamers, small …

The use of RNA interference (RNAi) is spreading rapidly to nearly every aspect of
biomedical research. The gene silencing capability of RNAi is being used to study individual …

Small interfering RNA (siRNA) is a potential method of gene silencing to target specific
genes. Although the US Food and Drug Administration (FDA) has approved multiple siRNA …

Since the revolutionary discovery of RNA interference (RNAi), a remarkable progress has
been achieved in understanding and harnessing gene silencing mechanism; especially in …

RNA interference (RNAi) is an endogenous post-transcriptional gene regulatory mechanism,
where non-coding, double-stranded RNA molecules interfere with the expression of certain …