Citrus fruits and their flavonoids in inflammatory bowel disease: an overview

L Musumeci, A Maugeri, S Cirmi… - Natural Product …, 2020 - Taylor & Francis
Inflammatory bowel disease (IBD), with its major manifestations being Crohn's disease and
ulcerative colitis, belongs to the gastrointestinal inflammatory disorders, whose main …

Citrus aurantium L. and Its Flavonoids Regulate TNBS-Induced Inflammatory Bowel Disease through Anti-Inflammation and Suppressing Isolated Jejunum …

W He, Y Li, M Liu, H Yu, Q Chen, Y Chen… - International journal of …, 2018 - mdpi.com
Inflammatory bowel disease (IBD) is a serious digestive system disease, for which the
clinical therapeutic choices remain limited. Dried fruits of Citrus aurantium L.(CAL) are a …

Citrus flavonoids and the intestinal barrier: Interactions and effects

M Wang, H Zhao, X Wen, CT Ho… - … Reviews in Food Science …, 2021 - Wiley Online Library
The intestinal barrier plays a central role in sustaining gut homeostasis and, when
dysfunctional, may contribute to diseases. Dietary flavonoids derived from Citrus genus …

Flavonoids in inflammatory bowel disease: a review

T Vezza, A Rodríguez-Nogales, F Algieri, MP Utrilla… - Nutrients, 2016 - mdpi.com
Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the intestine
that compromises the patients' life quality and requires sustained pharmacological and …

Intestinal anti-inflammatory activity of red wine extract: Unveiling the mechanisms in colonic epithelial cells

C Nunes, E Ferreira, V Freitas, L Almeida… - Food & function, 2013 - pubs.rsc.org
The development of new therapeutic approaches, combining efficacy and safety against
intestinal inflammation, notably inflammatory bowel disease (IBD), has emerged as an …

Antioxidant and Anti-Inflammatory Activity of Citrus Flavanones Mix and Its Stability after In Vitro Simulated Digestion

M Denaro, A Smeriglio, D Trombetta - Antioxidants, 2021 - mdpi.com
Recently, several studies have highlighted the role of Citrus flavanones in counteracting
oxidative stress and inflammatory response in bowel diseases. The aim of study was to …

Immunomodulatory effects of flavonoids in the prophylaxis and treatment of inflammatory bowel diseases: a comprehensive review

D Ribeiro, C Proenca, S Rocha… - Current medicinal …, 2018 - ingentaconnect.com
Inflammatory Bowel Diseases (IBD) comprised of two disorders of idiopathic chronic
intestinal inflammation that affect about three million people worldwide: Crohn's disease and …

Gut microbiota modulation and anti-inflammatory properties of dietary polyphenols in IBD: New and consolidated perspectives

A Santino, A Scarano, S De Santis… - Current …, 2017 - ingentaconnect.com
Background: Polyphenols represent a great variety of compounds occurring in fruits,
vegetables and plant-derived products. Dietary polyphenols have been found displaying …

Anti-inflammatory protection afforded by cyanidin-3-glucoside and resveratrol in human intestinal cells via Nrf2 and PPAR-γ: Comparison with 5-aminosalicylic acid

D Serra, LM Almeida, TCP Dinis - Chemico-biological interactions, 2016 - Elsevier
This study investigated the involvement of nuclear factor erythroid 2 (Nrf2) and peroxisome
proliferator-activated receptor-gamma (PPAR-γ) pathways in the protection afforded by two …

A mechanistic review on plant-derived natural compounds as dietary supplements for prevention of inflammatory bowel disease

MH Farzaei, R Bahramsoltani… - Expert Review of …, 2016 - Taylor & Francis
Inflammatory bowel disease (IBD) is a recurrent idiopathic inflammatory condition,
characterized by disruption of the gut mucosal barrier. This mechanistic review aims to …