Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) is an important mediators of T-cell
activation in autoimmune diseases. The association of polymorphisms of CTLA gene with …

In the past decade, a number of case–control studies have been carried out to investigate
the relationship between the CTLA4 gene polymorphisms and type 1 diabetes (T1D) …

To evaluate the association between costimulatory molecule cytotoxic T-lymphocyte-
associated antigen-4 (CTLA-4) gene polymorphism and type 1 diabetes mellitus (T1DM) …

Background:+ 49A/G polymorphism of the cytotoxic T-lymphocyte-associated antigen-4
gene (CTLA-4) has been associated with type 1 diabetes (T1D). However, results were …

The authors performed a meta-analysis of 33 studies examining the association of type 1
diabetes mellitus with polymorphisms in the cytotoxic T-lymphocyte-associated antigen-4 …

In addition to HLA and insulin genes, the costimulatory molecule CTLA-4 gene is a
confirmed type 1 diabetes (T1D) susceptibility gene. Previous studies investigated the …

The cytotoxic T lymphocyte antigen-4 (CTLA-4) molecule is an important regulator of T-cell
activation and a susceptibility candidate for autoimmune diseases. To evaluate the impact of …

Background T1DM is a chronic organ-specific T-cell-mediated autoimmune disease
characterized by the selective destruction of β-cells in the islets of Langerhans, resulting in …

Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) is a protein receptor that
downregulates the immune system. CTLA4 gene variants associate with various …

BACKGROUND: Cytotoxic T lymphocyte antigen-4 (CTLA-4) molecule is an important
regulator of T cell activation involved in the down-regulation of immune response …