Stereotactic radiation for the comprehensive treatment of oligometastases (SABR-COMET): extended long-term outcomes

S Harrow, DA Palma, R Olson, S Gaede… - International Journal of …, 2022 - Elsevier
Purpose Long-term randomized data assessing the effect of ablative therapies in patients
with oligometastases are lacking. The Stereotactic Ablative Radiotherapy for the …

A review of ongoing trials of stereotactic ablative radiotherapy for oligometastatic cancers: Where will the evidence lead?

F Al-Shafa, AJ Arifin, GB Rodrigues, DA Palma… - Frontiers in …, 2019 - frontiersin.org
Purpose: The oligometastatic state is a proposed entity between localized cancer and widely
metastatic disease, comprising an intermediate subset of metastatic cancer patients. Most …

Stereotactic ablative radiotherapy for the comprehensive treatment of oligometastatic cancers: long-term results of the SABR-COMET phase II randomized trial

DA Palma, R Olson, S Harrow, S Gaede… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE The oligometastatic paradigm hypothesizes that patients with a limited number of
metastases may achieve long-term disease control, or even cure, if all sites of disease can …

New strategies in stereotactic radiotherapy for oligometastases

DA Palma, AV Louie, GB Rodrigues - Clinical Cancer Research, 2015 - AACR
Patients with metastatic solid tumors are usually treated with palliative intent. Systemic
therapy and palliative radiation are often used, with the goals of prolonging survival or …

Stereotactic ablative radiotherapy for the comprehensive treatment of 1–3 Oligometastatic tumors (SABR-COMET-3): study protocol for a randomized phase III trial

R Olson, L Mathews, M Liu, D Schellenberg, B Mou… - BMC cancer, 2020 - Springer
Background A recent randomized phase II trial evaluated stereotactic ablative radiotherapy
(SABR) in a group of patients with a small burden of oligometastatic disease (mostly with 1 …

Stereotactic ablative radiotherapy for comprehensive treatment of oligometastatic tumors (SABR-COMET): study protocol for a randomized phase II trial

DA Palma, CJA Haasbeek, GB Rodrigues, M Dahele… - BMC cancer, 2012 - Springer
Background Stereotactic ablative radiotherapy (SABR) has emerged as a new treatment
option for patients with oligometastatic disease. SABR delivers precise, high-dose …

Stereotactic ablative radiotherapy for the comprehensive treatment of 4–10 oligometastatic tumors (SABR-COMET-10): study protocol for a randomized phase III trial

DA Palma, R Olson, S Harrow, RJM Correa… - BMC cancer, 2019 - Springer
Background Stereotactic ablative radiotherapy (SABR) has emerged as a new treatment
option for patients with oligometastatic disease. SABR delivers precise, high-dose …

Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open …

DA Palma, R Olson, S Harrow, S Gaede, AV Louie… - The Lancet, 2019 - thelancet.com
Background The oligometastatic paradigm suggests that some patients with a limited
number of metastases might be cured if all lesions are eradicated. Evidence from …

Initial results of a multicenter phase 2 trial of stereotactic ablative radiation therapy for oligometastatic cancer

P Sutera, DA Clump, R Kalash, D D'Ambrosio… - International Journal of …, 2019 - Elsevier
Purpose Oligometastatic disease has emerged as a potentially curable state in the spectrum
of cancer progression. Aggressive local therapy such as stereotactic ablative radiation …

[HTML][HTML] Stereotactic radiotherapy for oligometastatic cancer: a prognostic model for survival

T de Vin, B Engels, T Gevaert, G Storme, M De Ridder - Annals of oncology, 2014 - Elsevier
Background Stereotactic radiotherapy (SRT) is a safe and locally effective treatment for
patients with inoperable oligometastases. The challenge remains identifying subsets of …