Anthropomorphic model of intrathecal cerebrospinal fluid dynamics within the spinal subarachnoid space: spinal cord nerve roots increase steady-streaming

M Khani, LR Sass, T Xing… - Journal of …, 2018 - asmedigitalcollection.asme.org
Cerebrospinal fluid (CSF) dynamics are thought to play a vital role in central nervous system
(CNS) physiology. The objective of this study was to investigate the impact of spinal cord …

Nonuniform moving boundary method for computational fluid dynamics simulation of intrathecal cerebrospinal flow distribution in a cynomolgus monkey

M Khani, T Xing, C Gibbs… - Journal of …, 2017 - asmedigitalcollection.asme.org
A detailed quantification and understanding of cerebrospinal fluid (CSF) dynamics may
improve detection and treatment of central nervous system (CNS) diseases and help …

A computational model for the dynamics of cerebrospinal fluid in the spinal subarachnoid space

EF Toro, B Thornber, Q Zhang… - Journal of …, 2019 - asmedigitalcollection.asme.org
Global models for the dynamics of coupled fluid compartments of the central nervous system
(CNS) require simplified representations of the individual components which are both …

Characterization of the discrepancies between four-dimensional phase-contrast magnetic resonance imaging and in-silico simulations of cerebrospinal fluid dynamics

S Heidari Pahlavian, AC Bunck… - Journal of …, 2015 - asmedigitalcollection.asme.org
The purpose of the present study was to compare subject-specific magnetic resonance
imaging (MRI)-based computational fluid dynamics (CFD) simulations with time-resolved …

A poroelastic fluid/structure-interaction model of cerebrospinal fluid dynamics in the cord with syringomyelia and adjacent subarachnoid-space stenosis

CD Bertram, M Heil - Journal of Biomechanical …, 2017 - asmedigitalcollection.asme.org
An existing axisymmetric fluid/structure-interaction (FSI) model of the spinal cord, pia mater,
subarachnoid space, and dura mater in the presence of syringomyelia and subarachnoid …

Evaluation by fluid/structure-interaction spinal-cord simulation of the effects of subarachnoid-space stenosis on an adjacent syrinx

CD Bertram - Journal of biomechanical engineering, 2010 - asmedigitalcollection.asme.org
A finite-element numerical model was constructed of the spinal cord, pia mater, filum
terminale, cerebrospinal fluid in the spinal subarachnoid space (SSS), and dura mater. The …

Cerebrospinal fluid pressures resulting from experimental traumatic spinal cord injuries in a pig model

CF Jones, JHT Lee, U Burstyn… - Journal of …, 2013 - asmedigitalcollection.asme.org
Despite considerable effort over the last four decades, research has failed to translate into
consistently effective treatment options for spinal cord injury (SCI). This is partly attributed to …

Impact of Neurapheresis system on intrathecal cerebrospinal fluid dynamics: a computational fluid dynamics study

M Khani, LR Sass, AR McCabe… - Journal of …, 2020 - asmedigitalcollection.asme.org
It has been hypothesized that early and rapid filtration of blood from cerebrospinal fluid
(CSF) in postsubarachnoid hemorrhage patients may reduce hospital stay and related …

Biomechanical behaviors in three types of spinal cord injury mechanisms

B Khuyagbaatar, K Kim… - Journal of …, 2016 - asmedigitalcollection.asme.org
Clinically, spinal cord injuries (SCIs) are radiographically evaluated and diagnosed from
plain radiographs, computed tomography (CT), and magnetic resonance imaging. However …

An in vitro assessment of the cerebral hemodynamics through three patient specific circle of Willis geometries

P Fahy, P Delassus, P McCarthy… - Journal of …, 2014 - asmedigitalcollection.asme.org
The Circle of Willis (CoW) is a complex pentagonal network comprised of fourteen cerebral
vessels located at the base of the brain. The collateral flow feature within the circle of Willis …