Mass spectrometry imaging and its application in pharmaceutical research and development: A concise review
JG Swales, G Hamm, MR Clench… - International Journal of …, 2019 - Elsevier
Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …
Mass spectrometry imaging for drug distribution studies
B Prideaux, M Stoeckli - Journal of proteomics, 2012 - Elsevier
Since its introduction mass spectrometry imaging (MSI) has proven to be a powerful tool for
the localization of molecules in biological tissues. In drug discovery and development …
the localization of molecules in biological tissues. In drug discovery and development …
Qualitative and quantitative mass spectrometry imaging of drugs and metabolites
CB Lietz, E Gemperline, L Li - Advanced drug delivery reviews, 2013 - Elsevier
Mass spectrometric imaging (MSI) has rapidly increased its presence in the pharmaceutical
sciences. While quantitative whole-body autoradiography and microautoradiography are the …
sciences. While quantitative whole-body autoradiography and microautoradiography are the …
Future technology insight: mass spectrometry imaging as a tool in drug research and development
In pharmaceutical research, understanding the biodistribution, accumulation and
metabolism of drugs in tissue plays a key role during drug discovery and development. In …
metabolism of drugs in tissue plays a key role during drug discovery and development. In …
Qualitative and quantitative mass spectrometry imaging of drugs and metabolites in tissue at therapeutic levels
N Sun, A Walch - Histochemistry and Cell Biology, 2013 - Springer
Mass spectrometry imaging (MSI) is a rapidly evolving technology that yields qualitative and
quantitative distribution maps of small pharmaceutical-active molecules and their …
quantitative distribution maps of small pharmaceutical-active molecules and their …
A critical and concise review of mass spectrometry applied to imaging in drug discovery
RJA Goodwin, Z Takats… - … : Advancing the Science of …, 2020 - journals.sagepub.com
During the past decade, mass spectrometry imaging (MSI) has become a robust and
versatile methodology to support modern pharmaceutical research and development. The …
versatile methodology to support modern pharmaceutical research and development. The …
[HTML][HTML] Mass spectrometry imaging in drug distribution and drug metabolism studies–Principles, applications and perspectives
JR Granborg, AM Handler, C Janfelt - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
New mass spectrometry imaging (MSI) techniques are gaining importance in various stages
of the drug discovery and development chain as well as in more fundamental studies of drug …
of the drug discovery and development chain as well as in more fundamental studies of drug …
Current state and future challenges of mass spectrometry imaging for clinical research
RD Addie, B Balluff, JVMG Bovée, H Morreau… - 2015 - ACS Publications
The ability of mass spectrometry imaging (MSI) to localize panels of biomolecules in tissues,
without prior knowledge of their presence and in a label-free manner, has led to a rapid and …
without prior knowledge of their presence and in a label-free manner, has led to a rapid and …
Spatial analysis of drug absorption, distribution, metabolism, and toxicology using mass spectrometry imaging
ML Spruill, M Maletic-Savatic, H Martin, F Li… - Biochemical …, 2022 - Elsevier
Mass spectrometry imaging (MSI) is emerging as a powerful analytical tool for detection,
quantification, and simultaneous spatial molecular imaging of endogenous and exogenous …
quantification, and simultaneous spatial molecular imaging of endogenous and exogenous …
Quantitative mass spectrometry imaging of drugs and metabolites: a multiplatform comparison
L Lamont, D Hadavi, B Viehmann, B Flinders… - Analytical and …, 2021 - Springer
Mass spectrometry imaging (MSI) provides insight into the molecular distribution of a broad
range of compounds and, therefore, is frequently applied in the pharmaceutical industry …
range of compounds and, therefore, is frequently applied in the pharmaceutical industry …