Chronic inflammation is widely accepted to be an important cause of tumor formation and
development (1, 2). The primary significance of chronic inflammation in cancer may be in its …

Background: It is widely accepted that chronic inflammation critically contributes to cancer.
Immune tolerance in cancer mediates tumor escape from the immune system. The …

Inflammation has been recognized as an important driver in the development and growth of
malignancies. Inflammatory signaling in cancer emerges from the combinatorial interaction …

In the last decade, groundbreaking achievements have been obtained in the field of
oncology. These have been fueled by the strong belief that a better knowledge of genetic or …

Since it has become clear that tumor can be recognized and eliminated by the host immune
system, two main questions have confronted researchers and physicians: why the immune …

Recent literature has highlighted an important role of inflammation in promoting cancer.
However, the immune system can also play a central role in protecting the body against …

Tumour-promoting inflammation is considered one of the enabling characteristics of cancer
development. Chronic inflammatory disease increases the risk of some cancers, and strong …

The advent of high-throughput technology challenges the traditional histopathological
classification of cancer, and proposes new taxonomies derived from global transcriptional …

Inflammation is a hallmark of cancer and supports tumor growth, proliferation, and
metastasis, but also inhibits T cell immunosurveillance and the efficacy of immunotherapy …

Given the vast number of genetic and epigenetic changes associated with carcinogenesis, it
is clear that tumors express many neoantigens. A central question in cancer immunology is …