Urease, a nickel-dependent metalloenzyme, is synthesized by plants, some bacteria, and
fungi. It catalyzes the hydrolysis of urea into ammonia and carbon dioxide. Although the …

Background: Urease catalyzes the hydrolysis of urea, the final step of organic nitrogen
mineralization, using a bimetallic nickel centre. The role of the active site metal ions and …

Urease, the first enzyme to be crystallized, contains a dinuclear nickel metallocenter that
catalyzes the decomposition of urea to produce ammonia, a reaction of great agricultural …

Ureases (EC 3.5. 1.5) are nickel-dependent metalloenzymes that catalyze the hydrolysis of
urea to ammonia and carbon dioxide. Produced by plants, fungi and bacteria, but not by …

Abstract Urease (urea amidohydrolase, EC 3.5. 1.5) is a nickel-containing enzyme produced
by plants, fungi, and bacteria that catalyzes the hydrolysis of urea into ammonia and …

Urease from Klebsiella aerogenes [Jabri et al.(1995) Science 268, 998− 1004] is an (αβγ) 3
trimer with each α-subunit having an (αβ) 8-barrel domain containing a binickel active …

Proteus mirabilis, a common cause of urinary tract infection, produces a potent urease that
hydrolyzes urea to NH3 and CO2, initiating kidney stone formation. Urease genes, which …

The structure of β-mercaptoethanol-inhibited urease from Bacillus pasteurii, a highly
ureolytic soil micro-organism, was solved at 1.65 Å using synchrotron X-ray cryogenic …

Urease is a Ni (II)-containing enzyme that catalyzes the hydrolysis of urea to yield ammonia
and carbamate at a rate 10 15 times higher than the uncatalyzed reaction. Urease is a …

Urease, the most efficient enzyme known, contains an essential dinuclear NiII cluster in the
active site. It catalyzes the hydrolysis of urea, inducing a rapid pH increase that has negative …