ContextGlycemic disorders, one of the main risk factors for cardiovascular disease, are
associated with activation of oxidative stress. ObjectiveTo assess the respective …

Aims/hypothesis Glucose fluctuations may help predict diabetic complications. We evaluated
the relation between glucose variability and oxidative stress in patients with type 1 diabetes …

Aims/hypothesis We examined whether type of diabetes and/or insulin treatment can
modulate the impact of sustained hyperglycaemia and glycaemic variability as activators of …

In order to investigate whether short-or long-term glycemic fluctuations could induce
oxidative stress and chronic inflammation, we evaluated the relationships between glycemic …

The effect of glucose excursions on oxidative stress is an important topic in diabetes
research. We investigated this relationship by analyzing markers of oxidative stress and …

Chronic hyperglycemia, usually assessed from HbA1c determinations, results in excessive
glycation and generation of oxidative stress. As a consequence, chronic hyperglycemia has …

The dysglycemia of diabetes includes two components:(1) sustained chronic hyperglycemia
that exerts its effects through both excessive protein glycation and activation of oxidative …

OBJECTIVE Glucose fluctuations trigger activation of oxidative stress, a main mechanism
leading to secondary diabetes complications. We evaluated the relationship between …

Oxidative stress is increased in Type 2 diabetes and this appears to underlie the
development of diabetic complications. Increased oxidative stress is claimed to be triggered …

Diabetes is characterized by glycemic disorders that include both sustained chronic
hyperglycemia and acute glucose fluctuations. There is now cogent evidence for the …