Transposable elements: genome innovation, chromosome diversity, and centromere conflict

SJ Klein, RJ O'Neill - Chromosome Research, 2018 - Springer
Although it was nearly 70 years ago when transposable elements (TEs) were first
discovered “jumping” from one genomic location to another, TEs are now recognized as …

Centromere repeats: hidden gems of the genome

G Hartley, RJ O'Neill - Genes, 2019 - mdpi.com
Satellite DNAs are now regarded as powerful and active contributors to genomic and
chromosomal evolution. Paired with mobile transposable elements, these repetitive …

Evolutionary dynamics of transposable elements at the centromere

LH Wong, KHA Choo - TRENDS in Genetics, 2004 - cell.com
Transposable elements are the single most abundant class of genetic material in higher
eukaryotes. These elements show a genome-wide distribution but are found in …

Ten things you should know about transposable elements

G Bourque, KH Burns, M Gehring, V Gorbunova… - Genome biology, 2018 - Springer
Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense …

Mammalian transposable elements and their impacts on genome evolution

RN Platt, MW Vandewege, DA Ray - Chromosome Research, 2018 - Springer
Transposable elements (TEs) are genetic elements with the ability to mobilize and replicate
themselves in a genome. Mammalian genomes are dominated by TEs, which can reach …

Transposable elements and the epigenetic regulation of the genome

RK Slotkin, R Martienssen - Nature reviews genetics, 2007 - nature.com
Overlapping epigenetic mechanisms have evolved in eukaryotic cells to silence the
expression and mobility of transposable elements (TEs). Owing to their ability to recruit the …

Host–transposon interactions: conflict, cooperation, and cooption

RL Cosby, NC Chang, C Feschotte - Genes & development, 2019 - genesdev.cshlp.org
Transposable elements (TEs) are mobile DNA sequences that colonize genomes and
threaten genome integrity. As a result, several mechanisms appear to have emerged during …

Transposable elements in mammalian chromatin organization

HA Lawson, Y Liang, T Wang - Nature Reviews Genetics, 2023 - nature.com
Transposable elements (TEs) are mobile DNA elements that comprise almost 50% of
mammalian genomic sequence. TEs are capable of making additional copies of themselves …

Inviting instability: transposable elements, double-strand breaks, and the maintenance of genome integrity

DJ Hedges, PL Deininger - Mutation Research/Fundamental and Molecular …, 2007 - Elsevier
The ubiquity of mobile elements in mammalian genomes poses considerable challenges for
the maintenance of genome integrity. The predisposition of mobile elements towards …

Mobilizing diversity: transposable element insertions in genetic variation and disease

KA O'Donnell, KH Burns - Mobile DNA, 2010 - Springer
Transposable elements (TEs) comprise a large fraction of mammalian genomes. A number
of these elements are actively jumping in our genomes today. As a consequence, these …