Knockdown of TFAP2E results in rapid G2/M transition in oral squamous cell carcinoma cells

R Sakai, K Fujiwara… - Oncology …, 2024 - spandidos-publications.com
TFAP2E is a member of the activator protein‑2 transcription factor family and acts as a tumor
suppressor in several types of cancer. Downregulation of TFAP2E expression is significantly …

Overexpression of transcription factor activating enhancer binding protein 4 (TFAP4) predicts poor prognosis for colorectal cancer patients

J Wei, P Yang, T Zhang, Z Chen… - Experimental and …, 2017 - spandidos-publications.com
Transcription factor activating enhancer binding protein 4 (TFAP4) is an important regulator
in the genesis and progression of human cancers. Overexpression of TFAP4 has been …

[HTML][HTML] Evaluating the prognostic value and functional roles of transcription factor AP4 in colorectal cancer

J Yang, JP Ma, S Xiao, XH Zhang, JB Xu… - Oncology …, 2018 - spandidos-publications.com
The basic helix-loop-helix transcription factor AP4 (TFAP4) gene serves an important
function in the genesis and progression of tumors. However, few studies to date have …

Crucial role of the transcription factors family activator protein 2 in cancer: current clue and views

C Jin, Y Luo, Z Liang, X Li, D Kołat, L Zhao… - Journal of Translational …, 2023 - Springer
The transcription factor family activator protein 2 (TFAP2) is vital for regulating both
embryonic and oncogenic development. The TFAP2 family consists of five DNA-binding …

TFAP2A regulates nasopharyngeal carcinoma growth and survival by targeting HIF-1α signaling pathway

D Shi, F Xie, Y Zhang, Y Tian, W Chen, L Fu… - Cancer prevention …, 2014 - AACR
TFAP2A is a transcription factor that orchestrates a variety of cell processes, including cell
growth and tissue differentiation. However, the regulation of TFAP2A in human …

TFAP2A promotes cervical cancer via a positive feedback pathway with PD‑L1

J Yang, Y Gao, S Yao, S Wan… - Oncology Reports, 2023 - spandidos-publications.com
Transcription factor AP‑2 alpha (TFAP2A) is a critical cell growth regulator that is
overexpressed in various tumor tissues. However, its role in the development of cervical …

An integrated pan‐cancer analysis of TFAP4 aberrations and the potential clinical implications for cancer immunity

JN Liu, XS Kong, P Sun, R Wang, W Li… - Journal of Cellular and …, 2021 - Wiley Online Library
Studies have shown that transcription factor activating enhancer binding protein 4 (TFAP4)
plays a vital role in multiple types of cancer; however, the TFAP4 expression profile is still …

TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF/PEDF signaling

L Fu, K Shi, J Wang, W Chen, D Shi, Y Tian, W Guo… - Molecular Cancer, 2014 - Springer
Background TFAP2B is a member of the AP2 transcription factor family, which orchestrates a
variety of cell processes. However, the roles of TFAP2B in regulating carcinogenesis remain …

Comprehensive analysis of the expression and prognosis for TFAP2 in human lung carcinoma

C Cheng, Z Ai, L Zhao - Genes & genomics, 2020 - Springer
Background The TFAP2 family of transcription factors, regulating gene expression related to
vertebrate evolution, have been studied extensively in human cancer. However, the distinct …

TFAP2C-mediated upregulation of TGFBR1 promotes lung tumorigenesis and epithelial–mesenchymal transition

W Kim, EG Kim, S Lee, D Kim, J Chun… - … & molecular medicine, 2016 - nature.com
TFAP2C (transcription factor-activating enhancer-binding protein 2C) expression has been
positively correlated with poor prognosis in patients with certain types of cancer, but the …