The exosome journey: from biogenesis to uptake and intracellular signalling
S Gurung, D Perocheau, L Touramanidou… - Cell Communication and …, 2021 - Springer
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
Exosomes: biogenesis, biologic function and clinical potential
Y Zhang, Y Liu, H Liu, WH Tang - Cell & bioscience, 2019 - Springer
Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of
multivesicular bodies and the plasma membrane. They were shown to carry cell-specific …
multivesicular bodies and the plasma membrane. They were shown to carry cell-specific …
Exosomes: potential disease biomarkers and new therapeutic targets
Exosomes are extracellular vesicles released by cells, both constitutively and after cell
activation, and are present in different types of biological fluid. Exosomes are involved in the …
activation, and are present in different types of biological fluid. Exosomes are involved in the …
[HTML][HTML] Exosome theranostics: biology and translational medicine
C He, S Zheng, Y Luo, B Wang - Theranostics, 2018 - ncbi.nlm.nih.gov
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules,
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …
such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through …
Exosome: a new player in translational nanomedicine
H Aheget, M Tristán-Manzano, L Mazini… - Journal of Clinical …, 2020 - mdpi.com
Exosomes are extracellular vesicles released by the vast majority of cell types both in vivo
and ex vivo, upon the fusion of multivesicular bodies (MVBs) with the cellular plasma …
and ex vivo, upon the fusion of multivesicular bodies (MVBs) with the cellular plasma …
Challenges and opportunities in exosome research—Perspectives from biology, engineering, and cancer therapy
ABSTRACT Exosomes are small ($30–140 nm) lipid bilayer-enclosed particles of
endosomal origin. They are a subset of extracellular vesicles (EVs) that are secreted by most …
endosomal origin. They are a subset of extracellular vesicles (EVs) that are secreted by most …
Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials
AV Vlassov, S Magdaleno, R Setterquist… - Biochimica et Biophysica …, 2012 - Elsevier
BACKGROUND: Cells continuously secrete a large number of microvesicles,
macromolecular complexes, and small molecules into the extracellular space. Of the …
macromolecular complexes, and small molecules into the extracellular space. Of the …
Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes
Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids,
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …
[HTML][HTML] Signaling pathways in exosomes biogenesis, secretion and fate
L Urbanelli, A Magini, S Buratta, A Brozzi, K Sagini… - Genes, 2013 - mdpi.com
Exosomes are small extracellular vesicles (30–100 nm) derived from the endosomal system,
which have raised considerable interest in the last decade. Several studies have shown that …
which have raised considerable interest in the last decade. Several studies have shown that …
The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities
S Pant, H Hilton, ME Burczynski - Biochemical pharmacology, 2012 - Elsevier
Exosomes are bioactive vesicles derived from the cell's endosomal membrane system and
secreted into surrounding body fluids. Exosomes contain cell and cell-state specific cargos …
secreted into surrounding body fluids. Exosomes contain cell and cell-state specific cargos …