Autoantibodies and B Cells: The ABC of rheumatoid arthritis pathophysiology
M Volkov, KA van Schie… - Immunological …, 2020 - Wiley Online Library
Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. In
the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly …
the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly …
From risk to chronicity: evolution of autoreactive B cell and antibody responses in rheumatoid arthritis
HU Scherer, D van der Woude… - Nature Reviews …, 2022 - nature.com
The presence of disease-specific autoantibody responses and the efficacy of B cell-targeting
therapies in rheumatoid arthritis (RA) indicate a pivotal role for B cells in disease …
therapies in rheumatoid arthritis (RA) indicate a pivotal role for B cells in disease …
The B cell response to citrullinated antigens in the development of rheumatoid arthritis
HU Scherer, TWJ Huizinga, G Krönke… - Nature Reviews …, 2018 - nature.com
The immune response to citrullinated antigens is found almost exclusively in patients with
rheumatoid arthritis (RA). It is a dynamic response that expands before the onset of disease …
rheumatoid arthritis (RA). It is a dynamic response that expands before the onset of disease …
The role of autoantibodies in the pathophysiology of rheumatoid arthritis
V Derksen, TWJ Huizinga… - Seminars in …, 2017 - Springer
Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation.
The presence of autoantibodies in the sera of RA patients has provided many clues to the …
The presence of autoantibodies in the sera of RA patients has provided many clues to the …
Beyond citrullination: other post-translational protein modifications in rheumatoid arthritis
The presence of autoantibodies is one of the hallmarks of rheumatoid arthritis (RA). In the
past few decades, rheumatoid factors (autoantibodies that recognize the Fc-tail of …
past few decades, rheumatoid factors (autoantibodies that recognize the Fc-tail of …
Autoantibodies in rheumatoid arthritis: historical background and novel findings
Autoantibodies represent a hallmark of rheumatoid arthritis (RA), with the rheumatoid factor
(RF) and antibodies against citrullinated proteins (ACPA) being the most acknowledged …
(RF) and antibodies against citrullinated proteins (ACPA) being the most acknowledged …
B cells in rheumatoid arthritis
S Bugatti, V Codullo, R Caporali, C Montecucco - Autoimmunity reviews, 2007 - Elsevier
Though its etiology remains unknown thus far, the role that autoimmune processes play in
rheumatoid arthritis (RA) pathogenesis has been widely proven. Given the easier …
rheumatoid arthritis (RA) pathogenesis has been widely proven. Given the easier …
Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications
T Kissel, S Reijm, LM Slot, M Cavallari… - Annals of the …, 2020 - ard.bmj.com
Objective Autoantibodies against antigens carrying distinct post-translational modifications
(PTMs), such as citrulline, homocitrulline or acetyllysine, are hallmarks of rheumatoid …
(PTMs), such as citrulline, homocitrulline or acetyllysine, are hallmarks of rheumatoid …
Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition
K Amara, J Steen, F Murray, H Morbach… - Journal of Experimental …, 2013 - rupress.org
Antibodies targeting citrullinated proteins (ACPAs [anticitrullinated protein antibodies]) are
commonly found in patients with rheumatoid arthritis (RA), strongly associate with distinct …
commonly found in patients with rheumatoid arthritis (RA), strongly associate with distinct …
[HTML][HTML] Clinical and pathophysiologic relevance of autoantibodies in rheumatoid arthritis
SB Rocha, DC Baldo, LEC Andrade - Advances in Rheumatology, 2019 - SciELO Brasil
Rheumatoid arthritis (RA) is an autoimmune/inflammatory disease affecting 0.5 to 1% of
adults worldwide and frequently leads to joint destruction and disability. Early diagnosis and …
adults worldwide and frequently leads to joint destruction and disability. Early diagnosis and …
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