CircZNF609 regulates pulmonary fibrosis via miR-145-5p/KLF4 axis and its translation function

W Sun, S Zhou, L Peng, Y Liu, D Cheng… - Cellular & Molecular …, 2023 - Springer
Background Pulmonary fibrosis is a growing clinical problem that develops as a result of
abnormal wound healing, leading to breathlessness, pulmonary dysfunction and ultimately …

circHIPK3 regulates lung fibroblast-to-myofibroblast transition by functioning as a competing endogenous RNA

J Zhang, J Lu, H Xie, D Wang, H Ni, Y Zhu, L Ren… - Cell death & …, 2019 - nature.com
Myofibroblasts predominantly emerging through fibroblast-to-myofibroblast transition (FMT)
are considered to be the key collagen-producing cells in pulmonary fibrosis. Circular RNAs …

Crosstalk of mRNA, miRNA, lncRNA, and circRNA and their regulatory pattern in pulmonary fibrosis

C Li, Z Wang, J Zhang, X Zhao, P Xu, X Liu, M Li… - … Therapy-Nucleic Acids, 2019 - cell.com
Noncoding RNAs (ncRNAs), such as microRNA (miRNA), long ncRNA (lncRNA), and
circular RNA (circRNA), are regulators of important biological functions. Therefore …

Circ_0035796 depletion inhibits transforming growth factor-β1-induced pulmonary fibrosis in a miR-150-5p/L1CAM-dependent manner

J Li, X Chen, B Zhang, C Wang - Autoimmunity, 2023 - Taylor & Francis
Background: The pathogenesis of pulmonary fibrosis is not fully understood. Previous work
has demonstrated the important role of circular RNA (circRNA) in pulmonary fibrosis …

Circular RNA MKLN1 promotes epithelial-mesenchymal transition in pulmonary fibrosis by regulating the miR-26a/b-5p/CDK8 axis in human alveolar epithelial cells …

Y Zhu, X Meng, X Zhu, J Zhang, H Lv, F Wang… - Archives of …, 2024 - Springer
Pulmonary fibrosis involves destruction of the lung parenchyma and extracellular matrix
deposition. Effective treatments for pulmonary fibrosis are lacking and its pathogenesis is …

Circ_0007535 upregulates TGFBR1 to promote pulmonary fibrosis in TGF-β1-treated lung fibroblasts via sequestering miR-18a-5p

M Shen, X Wang, X Chang, Z Li, N Jiang, Z Han… - Autoimmunity, 2023 - Taylor & Francis
Circular RNAs (circRNAs) are functional molecules in all kinds of fibrosis diseases. The
current study was performed for the exploration of circ_0007535 in pulmonary fibrosis. RNA …

The combined effects of circular RNA methylation promote pulmonary fibrosis

S Wang, W Luo, J Huang, M Chen, J Ding… - American journal of …, 2022 - atsjournals.org
m6A (N 6-methyladenosine) is the most common type of RNA methylation modification,
mainly occurring on mRNA. Whether m6A-modified circular RNAs (circRNAs) are involved in …

[HTML][HTML] CircHIPK3 regulates pulmonary fibrosis by facilitating glycolysis in miR-30a-3p/FOXK2-dependent manner

Q Xu, D Cheng, G Li, Y Liu, P Li, W Sun… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Pulmonary fibrosis develops when myofibroblasts and extracellular matrix excessively
accumulate in the injured lung, but what drives fibrosis is not fully understood. Glycolysis has …

Investigation of circular RNAs and related genes in pulmonary fibrosis based on bioinformatics analysis

L Yang, X Liu, N Zhang, L Chen, J Xu… - Journal of Cellular …, 2019 - Wiley Online Library
Pulmonary fibrosis is a lethal inflammatory disease. In this study, we aimed to explore the
potential‐related circular RNAs (circRNAs) and genes that are associated with pulmonary …

hnRNPL-activated circANKRD42 back-splicing and circANKRD42-mediated crosstalk of mechanical stiffness and biochemical signal in lung fibrosis

P Xu, J Zhang, M Wang, B Liu, R Li, H Li, N Zhai, W Liu… - Molecular Therapy, 2022 - cell.com
Increasing circular RNAs (circRNAs) are involved in the progression of idiopathic pulmonary
fibrosis (IPF). However, circRNA biogenesis and circRNA-mediated crosstalk between …