[HTML][HTML] Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications
WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …
because of their high immunomodulation ability, tropism towards inflamed and injured …
Biodistribution of mesenchymal stem/stromal cells in a preclinical setting
L Sensebé, S Fleury-Cappellesso - Stem cells international, 2013 - Wiley Online Library
Due to their multi/pluripotency and immunosuppressive properties, mesenchymal
stem/stromal cells (MSCs) are important tools for treatment of immune disorders and tissue …
stem/stromal cells (MSCs) are important tools for treatment of immune disorders and tissue …
Mesenchymal stem/stromal cells: a new''cells as drugs''paradigm. Efficacy and critical aspects in cell therapy
L de Girolamo, E Lucarelli, G Alessandri… - Current …, 2013 - ingentaconnect.com
Mesenchymal stem cells (MSCs) were first isolated more than 50 years ago from the bone
marrow. Currently MSCs may also be isolated from several alternative sources and they …
marrow. Currently MSCs may also be isolated from several alternative sources and they …
[HTML][HTML] Therapeutic mesenchymal stem/stromal cells: value, challenges and optimization
M Najar, R Melki, F Khalife, L Lagneaux… - Frontiers in cell and …, 2022 - frontiersin.org
Cellular therapy aims to replace damaged resident cells by restoring cellular and molecular
environments suitable for tissue repair and regeneration. Among several candidates …
environments suitable for tissue repair and regeneration. Among several candidates …
[HTML][HTML] A brief overview of global trends in MSC-based cell therapy
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …
[HTML][HTML] Challenges and advances in clinical applications of mesenchymal stromal cells
T Zhou, Z Yuan, J Weng, D Pei, X Du, C He… - Journal of hematology & …, 2021 - Springer
Mesenchymal stromal cells (MSCs), also known as mesenchymal stem cells, have been
intensely investigated for clinical applications within the last decades. However, the majority …
intensely investigated for clinical applications within the last decades. However, the majority …
Revisiting the mesenchymal “stem vs. stromal” cell dichotomy and its implications for development of improved potency metrics
DG Phinney, R Hwa Lee, SV Boregowda - Stem Cells, 2023 - academic.oup.com
Mesenchymal stem/stromal cell (MSC)-based therapies have been evaluated in over 1500
human clinical trials for a diverse array of disease indication, but outcomes remain …
human clinical trials for a diverse array of disease indication, but outcomes remain …
[HTML][HTML] Mesenchymal stromal cell therapeutic delivery: translational challenges to clinical application
For several decades, multipotent mesenchymal stromal cells (MSCs) have been extensively
studied for their therapeutic potential across a wide range of diseases. In the preclinical …
studied for their therapeutic potential across a wide range of diseases. In the preclinical …
[HTML][HTML] Mesenchymal stem cells: a new trend for cell therapy
Mesenchymal stem cells (MSCs), the major stem cells for cell therapy, have been used in
the clinic for approximately 10 years. From animal models to clinical trials, MSCs have …
the clinic for approximately 10 years. From animal models to clinical trials, MSCs have …
[HTML][HTML] Mesenchymal stem/stromal cells: developmental origin, tumorigenesis and translational cancer therapeutics
C Li, H Zhao, B Wang - Translational oncology, 2021 - Elsevier
While a large and growing body of research has demonstrated that mesenchymal
stem/stromal cells (MSCs) play a dual role in tumor growth and inhibition, studies exploring …
stem/stromal cells (MSCs) play a dual role in tumor growth and inhibition, studies exploring …