Update on the role of non-opioids for postoperative pain treatment

SA Schug, A Manopas - Best practice & research Clinical anaesthesiology, 2007 - Elsevier
Non-opioids play an ever increasing role in the treatment of postoperative pain; either on
their own for mild to moderate pain or in combination with other analgesic approaches, in …

Post‐operative analgesic effects of paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review

JB Dahl, RV Nielsen, J Wetterslev… - Acta …, 2014 - Wiley Online Library
In contemporary post‐operative pain management, patients are most often treated with
combinations of non‐opioid analgesics, to enhance pain relief and to reduce opioid …

Dipyrone is the preferred nonopioid analgesic for the treatment of acute and chronic pain. A survey of clinical practice in German‐speaking countries

L Reist, J Erlenwein, W Meissner… - … journal of pain, 2018 - Wiley Online Library
Purpose Nonopioid analgesics are frequently used for the treatment of acute and chronic
pain. Dipyrone is an alternative to NSAID s and paracetamol, however, data on the …

Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs for the reduction in morphine-related side-effects after major surgery: a systematic …

E Maund, C McDaid, S Rice, K Wright… - British journal of …, 2011 - academic.oup.com
Non-opioid analgesics, paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs), or
cyclo-oxygenase 2 (COX-2) inhibitors are often given along with morphine as part of …

Efficacy of intravenous paracetamol compared to dipyrone and parecoxib for postoperative pain management after minor-to-intermediate surgery: a randomised …

G Brodner, W Gogarten, H Van Aken… - European Journal of …, 2011 - journals.lww.com
Methods Patients undergoing minor-to-intermediate surgery under general anaesthesia
were randomly assigned to receive infusions of paracetamol (1 g every 6 h), dipyrone (1 g …

Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain

CKS Ong, RA Seymour, P Lirk… - Anesthesia & Analgesia, 2010 - journals.lww.com
BACKGROUND: There has been a trend over recent years for combining a nonsteroidal
antiinflammatory drug (NSAID) with paracetamol (acetaminophen) for pain management …

Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side effects after major surgery: a …

C McDaid, E Maund, S Rice, K Wright… - Health Technol …, 2010 - emerald.com
Background Patient-controlled analgesia (PCA) is a mainstay in the control of pain after
major surgery. The drug most commonly used with PCA is morphine, but its administration …

Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review

M Hyllested, S Jones, JL Pedersen… - British journal of …, 2002 - academic.oup.com
Background. Quantitative reviews of postoperative pain management have demonstrated
that the number of patients needed to treat for one patient to achieve at least 50% pain relief …

Single-dose intravenous paracetamol or propacetamol for prevention or treatment of postoperative pain: a systematic review and meta-analysis

ED McNicol, A Tzortzopoulou… - British Journal of …, 2011 - academic.oup.com
Paracetamol is the most commonly prescribed analgesic for the treatment of acute pain. The
efficacy and safety of iv formulations of paracetamol is unclear. We performed a systematic …

[HTML][HTML] Opioid sparing strategies for perioperative pain management other than regional anaesthesia: a narrative review

B Ghai, A Jafra, N Bhatia, N Chanana… - Journal of …, 2022 - journals.lww.com
Opioids play a crucial role in pain management in spite of causing increased hospital
morbidity and related costs. It may also cause significant risks such as postoperative nausea …